Developing and Evaluating Interventions to Reduce Inappropriate Prescribing of Antibiotics in Primary Care (WIME)
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Purpose
- Do paper-based and web-based intervention modelling experiments (the methodology we are developing) identify the same predictors of GP behaviour regarding prescribing of antibiotics for upper respiratory tract infections?
- Can a web-based IME system provide trialists with richer and more predictive information upon which to base the development of behavioural change interventions than paper-based IME systems?
| Condition | Intervention |
|---|---|
|
Antibiotic Prescribing by GPs for URTI. |
Behavioral: Persuasive communication Behavioral: To be developed Behavioral: General intervention |
| Study Type: | Interventional |
| Study Design: | Allocation: Randomized Endpoint Classification: Efficacy Study Intervention Model: Parallel Assignment Masking: Double Blind (Subject, Outcomes Assessor) Primary Purpose: Health Services Research |
| Official Title: | Developing and Evaluating Interventions to Reduce Inappropriate Prescribing by General Practitioners of Antibiotics for Upper Respiratory Tract Infections: an RCT to Compare Paper-based and Web-based Modelling Experiments |
- Web-based IME: Behavioural intention and behavioural simulation [ Time Frame: Immediately after completion of questionnaire ] [ Designated as safety issue: No ]
- Email vs postal recruitment: number of GPs completing the first questionnaire [ Time Frame: Up to 4 weeks after original invitation was sent ] [ Designated as safety issue: No ]
| Enrollment: | 270 |
| Study Start Date: | November 2010 |
| Study Completion Date: | September 2012 |
| Primary Completion Date: | May 2012 (Final data collection date for primary outcome measure) |
| Arms | Assigned Interventions |
|---|---|
|
Experimental: Persuasive communication
The persuasive intervention aimed to reinforce the GP's beliefs about the positive consequences of managing sore throat without prescribing antibiotics.
|
Behavioral: Persuasive communication
The persuasive intervention aimed to reinforce the GP's beliefs about the positive consequences of managing sore throat without prescribing antibiotics.
|
|
Experimental: Alternative intervention
The form of this intervention is to be developed in early part of project.
|
Behavioral: To be developed
The new intervention, designed to take advantage of the possibilities offered by web-based delivery, will be designed using predictors identified from the first questionnaire and by using appropriate behaviour change techniques.
|
|
Active Comparator: General information
The comparator will be provision of general information about prescribing of antibiotics taken from recent reviews on antibiotic prescribing.
|
Behavioral: General intervention
The comparator will be provision of general information about prescribing of antibiotics taken from recent reviews on antibiotic prescribing.
|
Detailed Description:
The NHS needs effective quality improvement interventions to be put into clinical practice, which requires effective behaviour change interventions. Intervention modelling experiments (IMEs) are a way of exploring and refining an intervention before moving to a full-scale trial. They do this by delivering key elements of the intervention in a simulation that approximates clinical practice by, for example, presenting GPs with a clinical scenario about making a treatment decision. Earlier IMEs have been paper-based, which limits what can be done in the simulation.
Web-based IMEs provide the potential for better clinical simulations, which have the potential to lead to better interventions. The current proposal will run a full, web-based IME involving 250 GPs that will advance the methodology of IMEs by directly comparing results with an earlier paper-based IME. Moreover, the web-based IME will evaluate an intervention that can be put into a full-scale trial that aims to reduce antibiotic prescribing in primary care. Reducing inappropriate prescribing of antibiotics in general practice is a national priority; indeed, antibiotic use is increasing in the UK and Scotland's prescribing is second highest amongst UK administrations. More effective behaviour change interventions are needed and this proposal will develop one such intervention and a system to model and test future interventions. This system will be applicable to any situation in the NHS where behaviour needs to be modified, including interventions aimed directly at the public.
Eligibility| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- GPs in Scotland.
Exclusion Criteria:
- Unable to obtain both an email address and a postal address for the GP.
Contacts and Locations| United Kingdom | |
| University of Dundee | |
| Dundee, Tayside, United Kingdom, DD1 4HN | |
| Principal Investigator: | Shaun Treweek, PhD | University of Dundee |
More Information
Publications:
| Responsible Party: | Shaun Treweek, Senior Lecturer, University of Dundee |
| ClinicalTrials.gov Identifier: | NCT01206738 History of Changes |
| Other Study ID Numbers: | 2010PS10, CZH/4/610 |
| Study First Received: | September 21, 2010 |
| Last Updated: | April 12, 2013 |
| Health Authority: | UK: Research Ethics Committee UK: NHS R&D Offices |
Additional relevant MeSH terms:
|
Respiratory Tract Infections Common Cold Infection Respiratory Tract Diseases Picornaviridae Infections RNA Virus Infections |
Virus Diseases Anti-Bacterial Agents Anti-Infective Agents Therapeutic Uses Pharmacologic Actions |
ClinicalTrials.gov processed this record on May 19, 2013