Metformin for Treatment Antipsychotic Induced Amenorrhea in Female Schizophrenic Patients
Antipsychotics such as risperidone could induce amenorrhea in schizophrenic patients. The investigators conducted a randomized, placebo-controlled study to test the efficacy of metformin for antipsychotic induced amenorrhea in schizophrenia patients.
|Study Design:||Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)
|Official Title:||Metformin for Treatment Antipsychotic Induced Amenorrhea in Female Schizophrenic Patients: a Double Blind, Placebo-controlled Study|
- prolactin level [ Designated as safety issue: No ]the outcome measure assess a efficacy.
- fasting glucose [ Designated as safety issue: Yes ]
|Study Start Date:||June 2008|
|Study Completion Date:||March 2010|
|Primary Completion Date:||January 2010 (Final data collection date for primary outcome measure)|
Please refer to this study by its ClinicalTrials.gov identifier: NCT01206153
|Institute of Mental Health of The Second Xiangya Hospital, Central South University|
|Changsha, Hunan, China, 410011|
|Principal Investigator:||Jingping Zhao, MD||Institute of Mental Health of The Second Xiangya Hospital, Central South University, 139# Renmin Middle Road，Changsha 410011, Hunan, P.R. China|