Comparing Outcomes of Elbow Extension Tendon Transfers
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Purpose
Active elbow extension has significant functional benefits for individuals with tetraplegia. The proposed work will provide information to assess how effectively people are using their elbow extension tendon transfers, and whether one surgery works more effectively than the other. This study will provide recommendations to clinicians about the possibility of improving function after surgery using rehab techniques.
| Condition |
|---|
|
Cervical Spinal Cord Injury |
| Study Type: | Observational |
| Study Design: | Observational Model: Cohort Time Perspective: Retrospective |
| Official Title: | A Comparison of Two Surgical Procedures That Restore Elbow Extension |
- Elbow extension strength [ Time Frame: At least one year post surgery ] [ Designated as safety issue: No ]
| Estimated Enrollment: | 45 |
| Study Start Date: | August 2011 |
| Estimated Study Completion Date: | September 2014 |
| Estimated Primary Completion Date: | June 2014 (Final data collection date for primary outcome measure) |
| Groups/Cohorts |
|---|
|
Group 1
Subjects with posterior deltoid-to-triceps tendon transfers
|
|
Group 2
Subjects with biceps-to-triceps tendon transfers
|
|
Group 3
Subjects with cervical SCI who have not had tendon transfers
|
Detailed Description:
Voluntary control of elbow extension significantly improves functional abilities for individuals with tetraplegia. As a result, surgical reconstruction of elbow extension via tendon transfer is considered a fundamental intervention that benefits the patient, even if other tendon transfers aimed at improving hand function are never performed. Presently, there are two common tendon transfer surgeries used to restore elbow extension following spinal cord injury. These are the posterior deltoid to triceps transfer and the biceps to triceps transfer. Both surgeries significantly improve voluntary elbow extension, although there is variability in the amount of control that is restored among patients. This study will directly compare the performance of the posterior deltoid transfer to the biceps transfer with regard to: voluntary elbow extension strength, the ability to activate the transfer, and neural factors associated with voluntary and involuntary control of individual muscles. These comparisons will be made in functionally relevant postures and will provide fundamental information that will improve clinical understanding of the capacity of each of these two procedures to restore elbow extension.
The fundamental hypothesis of this proposal is that an inability to maximally activate the transferred posterior deltoid and the transferred biceps significantly limits the elbow extension moment that can be produced.
Eligibility| Ages Eligible for Study: | 18 Years to 60 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Non-Probability Sample |
Three groups of subjects will be recruited to participate in the experiments: individuals that have had the posterior deltoid to triceps tendon transfer, individuals that have the biceps to triceps tendon transfer, and individuals with SCI between C5-C7 who have not had tendon transfers. Nominally, we plan to recruit 15 subjects from each group.
Inclusion Criteria:
- Cervical Spinal Cord Injury (C5-C7)
- Posterior Deltoid to Triceps Tendon Transfer at least one year post-surgery
- Biceps to Triceps Tendon Transfer at least one year post-surgery
Exclusion Criteria:
Subjects will be excluded from the studies if there is presence of concurrent severe medical illness, including:
- unhealed decubiti
- use of baclofen pumps
- existing infection
- cardiovascular disease
- significant osteoporosis (as indicated by a history of fractures following injury)
- or a history of pulmonary complications or autonomic dysreflexia
Contacts and Locations| Contact: Carrie Peterson | (312) 238-1416 | carrie.peterson4@va.gov |
| Contact: Wendy M Murray, PhD | (708) 202-8387 ext 25691 | Wendy.Murray@va.gov |
| United States, Illinois | |
| Edward Hines, Jr. VA Hospital | Recruiting |
| Hines, Illinois, United States, 60141-5000 | |
| Contact: Carrie Peterson 312-238-1416 carrie.peterson4@va.gov | |
| Principal Investigator: Wendy M Murray, PhD | |
| Principal Investigator: | Wendy M Murray, PhD | Edward Hines Jr. VA Hospital |
More Information
No publications provided
| Responsible Party: | Department of Veterans Affairs |
| ClinicalTrials.gov Identifier: | NCT01204736 History of Changes |
| Other Study ID Numbers: | B7515-R |
| Study First Received: | September 15, 2010 |
| Last Updated: | May 3, 2013 |
| Health Authority: | United States: Federal Government |
Keywords provided by Department of Veterans Affairs:
|
tendon transfer elbow |
Additional relevant MeSH terms:
|
Spinal Cord Injuries Spinal Cord Diseases Central Nervous System Diseases |
Nervous System Diseases Trauma, Nervous System Wounds and Injuries |
ClinicalTrials.gov processed this record on May 22, 2013