Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH)

This study is enrolling participants by invitation only.
Sponsor:
Collaborators:
Massachusetts General Hospital
Columbia University
University of Maryland
Georgetown University
Wake Forest School of Medicine
Emory University
University of Miami
University of Illinois at Chicago
University of Texas, Southwestern Medical Center at Dallas
The University of Texas Health Science Center, Houston
The University of Texas Health Science Center at San Antonio
University of New Mexico
University of Arizona
University of Southern California
St. Luke
UCSF - Fresno
Duke University
University of Virginia
Information provided by (Responsible Party):
Daniel Woo, University of Cincinnati
ClinicalTrials.gov Identifier:
NCT01202864
First received: September 14, 2010
Last updated: May 19, 2014
Last verified: May 2014
  Purpose

The purpose of this study is to find risk factors for hemorrhagic stroke, specifically intracerebral hemorrhage (ICH), among Caucasians, African Americans, and Hispanics.


Condition
Intracerebral Hemorrhage

Study Type: Observational
Study Design: Observational Model: Case Control
Official Title: Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH)

Resource links provided by NLM:


Further study details as provided by University of Cincinnati:

Biospecimen Retention:   Samples With DNA

whole blood


Estimated Enrollment: 6000
Study Start Date: August 2010
Estimated Study Completion Date: March 2015
Estimated Primary Completion Date: March 2015 (Final data collection date for primary outcome measure)
Groups/Cohorts
Cases
3000 Cases
Controls
3000 Controls

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Our purpose is to enroll 1000 cases of ICH among whites, 1000 cases of ICH among blacks, and 1000 cases of ICH among Hispanics.

3000 controls matched to cases by race/ethnicity, age (+/- 5 years), gender, and geographic location.

Criteria

Inclusion Criteria:

All cases must meet the following eligibility criteria:

  1. Age 18 years or greater, fulfillment of the criteria for intracerebral hemorrhage
  2. Resident for at least 6 months within 50 miles of the recruiting center
  3. No evidence of trauma, vascular malformation or aneurysm, or brain tumor as a cause of the hemorrhage
  4. Ability of the patient or legal representative to provide informed consent

Exclusion Criteria:

Exclusion Criteria:

  1. Malignancies leading to coagulopathy
  2. Hemorrhagic transformation of ischemic infarct
  3. Hemorrhage secondary to dural venous sinus thrombosis
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01202864

Locations
United States, Arizona
University of Arizona
Tucson, Arizona, United States, 85724
United States, California
University of Southern California
Los Angeles, California, United States, 90033
United States, District of Columbia
Georgetown University
Washington, District of Columbia, United States, 20007
United States, Florida
University of Miami
Miami, Florida, United States, 33136
University of Miami - Biorepository
Miami, Florida, United States, 33136
United States, Georgia
Emory University
Atlanta, Georgia, United States, 30303
United States, Illinois
University of Illinois
Chicago, Illinois, United States, 60612
United States, Maryland
University of Maryland
Baltimore, Maryland, United States, 21201
United States, Massachusetts
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
United States, New Mexico
University of New Mexico
Albuquerque, New Mexico, United States, 87131
United States, New York
Columbia University
New York City, New York, United States, 10032
United States, North Carolina
Wake Forest University
Winston-Salem, North Carolina, United States, 27157
United States, Texas
University of Texas Southwestern Medical Center at Dallas
Dallas, Texas, United States, 75390
University of Texas Medical School at Houston
Houston, Texas, United States, 77030
University of Texas Health Science Center at San Antonio
San Antonio, Texas, United States, 78229
Sponsors and Collaborators
University of Cincinnati
Massachusetts General Hospital
Columbia University
University of Maryland
Georgetown University
Wake Forest School of Medicine
Emory University
University of Miami
University of Illinois at Chicago
University of Texas, Southwestern Medical Center at Dallas
The University of Texas Health Science Center, Houston
The University of Texas Health Science Center at San Antonio
University of New Mexico
University of Arizona
University of Southern California
St. Luke
UCSF - Fresno
Duke University
University of Virginia
Investigators
Principal Investigator: Daniel Woo, MD, MS University of Cincinnati
Principal Investigator: Matthew Flaherty, MD University of Cincinnati
  More Information

Publications:

Responsible Party: Daniel Woo, Professor, University of Cincinnati
ClinicalTrials.gov Identifier: NCT01202864     History of Changes
Other Study ID Numbers: 1008059, R01NS069763-01
Study First Received: September 14, 2010
Last Updated: May 19, 2014
Health Authority: United States: Institutional Review Board

Keywords provided by University of Cincinnati:
Intracerebral Hemorrhage
ICH
Stroke
CVA

Additional relevant MeSH terms:
Hemorrhage
Cerebral Hemorrhage
Pathologic Processes
Intracranial Hemorrhages
Cerebrovascular Disorders
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Vascular Diseases
Cardiovascular Diseases

ClinicalTrials.gov processed this record on September 18, 2014