Tumorspecific T-cell Immunity in Bladder Cancer as Prognostic Marker
Bladder cancer is generally susceptible to immunotherapeutic measures. The investigators will characterize 40 patients with muscle-invasive bladder cancer regarding the existence and frequency of tumorspecific T-cells and regulatory T cells. The found data will be correlated to clinical data such as the cancer-specific survival and the response to chemotherapy.
It is hypothesized that those patients with a high number of Tregs and no tumor-specific T-cells have a worse prognosis.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Prospective Characterization of Tumor-specific T-cell Immunity in Muscle-invasive Bladder Cancer and Its Correlation With Clinical Parameters|
|Urologische Klinik der Technischen Universität München|
|Munich, Bavaria, Germany, 81675|
|Principal Investigator:||Thomas Horn, MD||Department of Urology, Technische Universität München|