Study: Effects of Strawberries on Blood Pressure (CSCBP)
The specific aim of the study is to determine whether a freeze dried powder provided by the California Strawberries Commission, can reduce blood pressure in patients with pre-hypertension. The powder is prepared by the California Strawberry Commission (CSC).
|Study Design:||Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Investigator)
Primary Purpose: Basic Science
|Official Title:||Effect of Strawberry Powder on Blood Pressure in Individuals With Pre-Hypertension|
- Change in blood pressure [ Time Frame: 8 weeks ] [ Designated as safety issue: No ]
- Change in low density lipoprotein (LDL) oxidation [ Time Frame: 8 weeks ] [ Designated as safety issue: No ]
- Change in flow mediated dilation (FMD) [ Time Frame: 8 weeks ] [ Designated as safety issue: No ]
|Study Start Date:||September 2007|
|Estimated Study Completion Date:||May 2012|
|Primary Completion Date:||October 2011 (Final data collection date for primary outcome measure)|
Placebo Comparator: Placebo Beverage
The placebo beverage is matched in energy, macronutrient composition and sensory properties to the active beverage, but is devoid of strawberry polyphenols.
Placebo beverage, 8 weeks
Other Name: Beverage
Experimental: Strawberry Beverage
The strawberry beverage is matched in energy, macronutrient composition and sensory properties to the placebo beverage, but contains strawberry polyphenols.
Other: Strawberry Beverage
Beverage, daily for 8 weeks, 12g freeze-dried strawberry powder
Other Name: Strawberry powder made from a mix of California strawberries.
Primarily, we would like to find out whether freeze dried strawberry powder lowers blood pressure. In addition we would like to know if the strawberry alters the subject's blood cholesterol and the ability of the subject's blood vessels to relax.
|United States, California|
|University of California Davis (Ragle Hall)|
|Davis, California, United States, 95616|
|Principal Investigator:||Chulani T Kappagoda, MD||University of California, Davis|
|Principal Investigator:||Britt Burton-Freeman, Ph.D||University of California, Davis|