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The Biodistribution of 1-L-(2 Deoxy-2,- 18 Fluoroarabinofuranosyl) Cytosine ([18F]L-FAC) in Healthy Subjects and Patients With Cancer, Autoimmune and Inflammatory Diseases

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Jonsson Comprehensive Cancer Center
ClinicalTrials.gov Identifier:
NCT01180868
First received: August 11, 2010
Last updated: July 27, 2012
Last verified: July 2012
History of Changes
  Purpose

The purpose of this study is to determine the biodistribution of a new agent 1-L-(2 deoxy-2,-18fluoroarabinofuranosyl) cytosine non-invasively in healthy humans and to evaluate whether it can be used to image cancer, autoimmune disease, and inflammation


Condition
Autoimmune Diseases
Cancer

Study Type: Observational
Official Title: The Biodistribution of 1-L-(2 Deoxy-2,- 18 Fluoroarabinofuranosyl) Cytosine ([18F]L-FAC) in Healthy Subjects and Patients With Cancer, Autoimmune and Inflammatory Diseases

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Jonsson Comprehensive Cancer Center:

Enrollment: 1
Study Start Date: May 2008
Primary Completion Date: November 2011 (Final data collection date for primary outcome measure)
Groups/Cohorts
patients with cancer
patients with hematological malignancies and solid tumors
patients with autoimmune dosorders
patients with Rheumatoid arthritis, Crohns's disease, systemic lupus erythematosus.
healthy subjects

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Patients with cancer, patients with autoimmune dosorders, and healthy subjects.

Criteria

Inclusion Criteria:

  • greater than 18 years of age
  • women of childbearing potential will undergo a pregnancy test free of charge
  • patients with hematological malignancies, solid tumors or autoimmune disorders
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01180868

Locations
United States, California
UCLA
Los Angeles, California, United States, 90095
Sponsors and Collaborators
Jonsson Comprehensive Cancer Center
Investigators
Principal Investigator: Christiaan Schiepers, M.D. Ph.D University of California, Los Angeles
  More Information

No publications provided

Responsible Party: Jonsson Comprehensive Cancer Center
ClinicalTrials.gov Identifier: NCT01180868     History of Changes
Other Study ID Numbers: 08-02-049, DE-PS02-08ER08-01, CIRM No. RT1-01126-1
Study First Received: August 11, 2010
Last Updated: July 27, 2012
Health Authority: United States: Institutional Review Board

Keywords provided by Jonsson Comprehensive Cancer Center:
imaging probe
cancer
inflammatory tissue
inflammatory diseases

Additional relevant MeSH terms:
Autoimmune Diseases
Immune System Diseases

ClinicalTrials.gov processed this record on May 16, 2013