Very-Low-Density-Lipoprotein-Triglyceride(VLDL-TG) Metabolism During Acute Hyperglycemia

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
University of Aarhus
ClinicalTrials.gov Identifier:
NCT01178957
First received: April 21, 2010
Last updated: August 5, 2013
Last verified: August 2013
  Purpose

The purpose of this study is to estimate the acute effect of hyperglycemia on Very-Low-Density-Lipoprotein-triglyceride(VLDL-TG) secretion.


Condition Intervention
Type 1 Diabetes
Other: Hyperglycemia

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Very-Low-Density-Lipoprotein-Triglyceride(VLDL-TG) Metabolism During Acute Hyperglycemia

Resource links provided by NLM:


Further study details as provided by University of Aarhus:

Primary Outcome Measures:
  • Very-Low-Density-Lipoprotein-Triglyceride(VLDL-TG) secretion [ Time Frame: 8 hours ] [ Designated as safety issue: No ]
    Very-Low-Density-Lipoprotein-Triglyceride(VLDL-TG) kinetics over a single study day


Biospecimen Retention:   Samples With DNA

Blood Samples


Enrollment: 8
Study Start Date: April 2012
Study Completion Date: April 2013
Primary Completion Date: April 2013 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Type 1 diabetes Other: Hyperglycemia
Hyperglycemia with a blood glucose of 15 mmol/L

  Eligibility

Ages Eligible for Study:   18 Years to 50 Years
Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Type 1 diabetics

Criteria

Inclusion Criteria:

  1. Type 1 diabetes
  2. Age 18-50 years

Exclusion Criteria:

  1. Smoking
  2. Alcohol abuse
  3. Use of medications (except insulin in diabetics)
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01178957

Locations
Denmark
Department of Endocrinology MEA, Aarhus Hospital
Aarhus C, Denmark, 8000
Sponsors and Collaborators
University of Aarhus
  More Information

No publications provided

Responsible Party: University of Aarhus
ClinicalTrials.gov Identifier: NCT01178957     History of Changes
Other Study ID Numbers: ES-0004
Study First Received: April 21, 2010
Last Updated: August 5, 2013
Health Authority: Denmark: Danish Dataprotection Agency

Keywords provided by University of Aarhus:
Type 1 diabetes
Very-Low-Density-Lipoprotein(VLDL)
Hyperglycemia

Additional relevant MeSH terms:
Diabetes Mellitus
Diabetes Mellitus, Type 1
Hyperglycemia
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases
Autoimmune Diseases
Immune System Diseases

ClinicalTrials.gov processed this record on April 23, 2014