Very-Low-Density-Lipoprotein-Triglyceride(VLDL-TG) Metabolism During Acute Hyperglycemia

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
University of Aarhus
ClinicalTrials.gov Identifier:
NCT01178957
First received: April 21, 2010
Last updated: August 5, 2013
Last verified: August 2013
  Purpose

The purpose of this study is to estimate the acute effect of hyperglycemia on Very-Low-Density-Lipoprotein-triglyceride(VLDL-TG) secretion.


Condition Intervention
Type 1 Diabetes
Other: Hyperglycemia

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Very-Low-Density-Lipoprotein-Triglyceride(VLDL-TG) Metabolism During Acute Hyperglycemia

Resource links provided by NLM:


Further study details as provided by University of Aarhus:

Primary Outcome Measures:
  • Very-Low-Density-Lipoprotein-Triglyceride(VLDL-TG) secretion [ Time Frame: 8 hours ] [ Designated as safety issue: No ]
    Very-Low-Density-Lipoprotein-Triglyceride(VLDL-TG) kinetics over a single study day


Biospecimen Retention:   Samples With DNA

Blood Samples


Enrollment: 8
Study Start Date: April 2012
Study Completion Date: April 2013
Primary Completion Date: April 2013 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Type 1 diabetes Other: Hyperglycemia
Hyperglycemia with a blood glucose of 15 mmol/L

  Eligibility

Ages Eligible for Study:   18 Years to 50 Years
Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Type 1 diabetics

Criteria

Inclusion Criteria:

  1. Type 1 diabetes
  2. Age 18-50 years

Exclusion Criteria:

  1. Smoking
  2. Alcohol abuse
  3. Use of medications (except insulin in diabetics)
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01178957

Locations
Denmark
Department of Endocrinology MEA, Aarhus Hospital
Aarhus C, Denmark, 8000
Sponsors and Collaborators
University of Aarhus
  More Information

No publications provided

Responsible Party: University of Aarhus
ClinicalTrials.gov Identifier: NCT01178957     History of Changes
Other Study ID Numbers: ES-0004
Study First Received: April 21, 2010
Last Updated: August 5, 2013
Health Authority: Denmark: Danish Dataprotection Agency

Keywords provided by University of Aarhus:
Type 1 diabetes
Very-Low-Density-Lipoprotein(VLDL)
Hyperglycemia

Additional relevant MeSH terms:
Diabetes Mellitus
Diabetes Mellitus, Type 1
Hyperglycemia
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases
Autoimmune Diseases
Immune System Diseases

ClinicalTrials.gov processed this record on August 20, 2014