Sonographic Differences in Brain Measurements Between Normal and Intrauterine Growth Restriction (IUGR) Fetuses

This study has been withdrawn prior to enrollment.
Sponsor:
Information provided by (Responsible Party):
Meir Medical Center
ClinicalTrials.gov Identifier:
NCT01178619
First received: August 8, 2010
Last updated: August 27, 2013
Last verified: August 2013
  Purpose

Intrauterine growth restriction is being suspected in cases where the fetal estimated weight is less then the 10 th percentile for its gestational age. Abdominal circumference is the most influenced measurement in this cases. Head circumference on the other hand can be or not be influenced. Previous studies have shown that transverse cerebellar diameter (TCD) is constant to gestational age and is not influenced by IUGR.Other showed lower TCD in IUGR fetuses. We would like to study the differences in cerebellar, vermian and corpus callosum growth between normal to IUGR fetuses and between symmetrical and asymmetrical IUGR. In this observational study we will include pregnant women between 28-37 gestational week with a singleton otherwise normal pregnancies. We will measure the fetal TCD, vermian distances and the CC, abdominal circumference, head circumference and femur length. we will compeer these measurements according to the following groups:normal fetuses, symmetrical and asymmetrical IUGR.


Condition
Intra-uterine Growth Restriction

Study Type: Observational
Study Design: Observational Model: Case Control

Further study details as provided by Meir Medical Center:

Enrollment: 0
Study Start Date: September 2010
Study Completion Date: August 2012
Estimated Primary Completion Date: August 2012 (Final data collection date for primary outcome measure)
Groups/Cohorts
AGA
symmetrical IUGR
asymmetrical IUGR

  Eligibility

Ages Eligible for Study:   28 Weeks to 37 Weeks
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population

pregnant women 28-37 GA, singleton, otherwise normal fetuses

Criteria

Inclusion Criteria:

  • singleton,
  • 28-37 GA,
  • well dated pregnancy.

Exclusion Criteria:

  • multifetal pregnancies,
  • no first trimester dating,
  • fetuses with known chromosomal or structural anomalies.
  Contacts and Locations
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No Contacts or Locations Provided
  More Information

No publications provided

Responsible Party: Meir Medical Center
ClinicalTrials.gov Identifier: NCT01178619     History of Changes
Other Study ID Numbers: MMC10095-2010CTIL
Study First Received: August 8, 2010
Last Updated: August 27, 2013
Health Authority: Israel: Ethics Commission

Keywords provided by Meir Medical Center:
IUGR fetuses
symmetrical IUGR
asymmetrical IUGR

Additional relevant MeSH terms:
Fetal Growth Retardation
Fetal Diseases
Pregnancy Complications
Growth Disorders
Pathologic Processes

ClinicalTrials.gov processed this record on July 23, 2014