The Effects of Three Oral Medications on Post-operative Pain Following Endodontic Treatment

This study has been completed.
Sponsor:
Information provided by:
Azad University of Medical Sciences
ClinicalTrials.gov Identifier:
NCT01178203
First received: August 9, 2010
Last updated: NA
Last verified: July 2010
History: No changes posted
  Purpose

Aim: eliminating or reducing pain following endodontic treatment is of great importance. The aim of this study is to compare the effects of Tramadol, Novafen and Naproxen on post-operative pain following instrumentation of root canals in teeth with irreversible pulpitis. Sample size: one hundred patients considering the inclusion and exclusion criteria were selected. Intervention and outcome: The effect of Tramadol, Novafen and Naproxen on post-operative pain following instrumentation of root canals in teeth with irreversible pulpitis was evaluated.


Condition Intervention Phase
Pulpitis
Pain Management
Drug: Placebo
Drug: Tramadol
Drug: Novafen
Drug: Naproxen
Phase 1
Phase 2

Study Type: Interventional
Study Design: Intervention Model: Parallel Assignment
Primary Purpose: Treatment

Resource links provided by NLM:


Further study details as provided by Azad University of Medical Sciences:

Study Start Date: July 2010
Study Completion Date: August 2010
Primary Completion Date: July 2010 (Final data collection date for primary outcome measure)
Intervention Details:
    Drug: Placebo
    Placebo
    Drug: Tramadol
    Tab, 100mg in 6, 12 and 24 hours after root canal treatment
    Drug: Novafen
    325 mg in 6, 12 and 24 hours after root canal treatment
    Drug: Naproxen
    Tab, 500 mg in 6, 12, and 24 hours after root canal treatment
  Eligibility

Ages Eligible for Study:   20 Years to 60 Years
Genders Eligible for Study:   Both
Criteria

Inclusion Criteria:

  1. The subjects were 20-60 years of age with no systemic diseases and females were not pregnant;
  2. No history of taking any analgesics or other drugs prior to presenting for treatment;
  3. Patients had moderate to severe pain associated with irreversible pulpitis in single-rooted premolars or anterior teeth.

Exclusion Criteria:

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

No Contacts or Locations Provided
  More Information

No publications provided

Responsible Party: Peyman Mehrvarzfar, Department of Endodontics, Dental School of Tehran Azad University of Medical Sciences
ClinicalTrials.gov Identifier: NCT01178203     History of Changes
Other Study ID Numbers: IAU-1083
Study First Received: August 9, 2010
Last Updated: August 9, 2010
Health Authority: Iran: Ministry of Health

Keywords provided by Azad University of Medical Sciences:
Endodontics
pain
visual analogue scale
NSAIDs

ClinicalTrials.gov processed this record on October 21, 2014