The Role of Routine Bacterial Culture Including Tuberculosis During Bronchoscopy: A Prospective Study
Many centers routinely culture bronchoscopy samples for bacteria and mycobacteria even when infections including tuberculosis (TB) are not strongly suspected. However, the value of this practice has been poorly defined.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||The Role of Routine Bacterial Culture Including Tuberculosis During|
- number of positive tuberculosis culture [ Time Frame: 12 months ] [ Designated as safety issue: No ]
|Study Start Date:||July 2010|
|Study Completion Date:||October 2012|
|Primary Completion Date:||October 2012 (Final data collection date for primary outcome measure)|
Many centers routinely culture bronchoscopy samples for bacteria and mycobacteria even when infections including tuberculosis (TB) are not strongly suspected. However, the value of this practice has been poorly defined. Unnecessary bronchial cultures of bacteria may lead to over treatment in patients without clinical evidence of infections and may increase the drug resistant strains.
In areas with a high prevalence of TB, routine bronchial cultures may detect clinically unsuspected TB in an appreciable proportion of cases. However, in population with a low prevalence of TB, routine culture of bronchial aspirates may incur an unnecessary expanse and may lead to over diagnosis and over treatment of patients with non pathogenic atypical mycobacteria detected by acid-fast bacillus strains.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01167647
|Pulmonary department, Meir Medical Center|
|Kfar Saba, Israel, 49100|
|Principal Investigator:||David Shitrit, MD||Meir Medical Center|