Eliminating Risk of Preventable Adverse Drug Events at the Hospital-community Interface of Care (CMR)

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Westview Physician Collaborative
ClinicalTrials.gov Identifier:
NCT01164137
First received: July 14, 2010
Last updated: February 12, 2013
Last verified: February 2013
  Purpose

This initiative aims to decrease the risk of medication errors at the hospital-community interface as well as health system utilization following hospital discharge by implementing a pharmacist-led medication reconciliation in the patients' home within 72 hours of hospital discharge.


Condition Intervention
Adverse Drug Events
Behavioral: Medication Reconciliation

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Health Services Research
Official Title: Eliminating Risk of Preventable Adverse Drug Events at the Hospital-community Interface of Care: to Develop and Test a Community-based Medication Reconciliation Program and a Risk Prediction Model That Identifies High-risk Patient Groups

Further study details as provided by Westview Physician Collaborative:

Primary Outcome Measures:
  • Health Services Utilization 3 Months Following Hospital Discharge [ Time Frame: 3 Months ] [ Designated as safety issue: Yes ]
    Mean health services utilization 3 months following hospital discharge. The specific health services utilization was re-admission to hospital, admission to home care, admission to long-term care and visits to emergency departments.

  • Health Services Utilization 6 Months Following Hospital Discharge [ Time Frame: 6 Months ] [ Designated as safety issue: Yes ]
    Mean health services utilization 6 months following hospital discharge. The specific health services utilization was re-admission to hospital, admission to home care, admission to long-term care and visits to emergency departments.

  • Health Services Utilization 9 Months Following Hospital Discharge [ Time Frame: 9 Months ] [ Designated as safety issue: Yes ]
    Mean health services utilization 9 months following hospital discharge. The specific health services utilization was re-admission to hospital, admission to home care, admission to long-term care and visits to emergency departments.

  • Health Services Utilization 12 Months Following Hospital Discharge [ Time Frame: 12 months ] [ Designated as safety issue: Yes ]
    Mean health services utilization 12 months following hospital discharge. The specific health services utilization was re-admission to hospital, admission to home care, admission to long-term care and visits to emergency departments.

  • Health Services Utilization 18 Months Following Hospital Discharge [ Time Frame: 18 months ] [ Designated as safety issue: Yes ]
    Mean health services utilization 18 months following hospital discharge. The specific health services utilization was re-admission to hospital, admission to home care, admission to long-term care and visits to emergency departments.


Enrollment: 156
Study Start Date: November 2008
Study Completion Date: February 2013
Primary Completion Date: February 2013 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Medication Reconciliation Intervention
Participants receiving a pharmacist-led home intervention conducted within 72 hours of hospital discharge aimed at identifying and correcting medication discrepancies.
Behavioral: Medication Reconciliation
A pharmacist-led home intervention conducted within 72 hours of hospital discharge aimed at correcting and identifying medication discrepancies.
No Intervention: Medication Reconciliation Non-Interven.
Participants not receiving a pharmacist-led home intervention conducted within 72 hours of hospital discharge aimed at identifying and correcting medication discrepancies.

Detailed Description:

The goals of this initiative are to decrease the risk for medication errors at the hospital community interface of care, thus decreasing preventable adverse drug events and preventable drug-related health system utilization following hospital discharge. This initiative has four objectives that aim to:

  1. Develop and test a community-based medication reconciliation process/intervention.
  2. Design and conduct a randomized controlled trial to examine the impact of the intervention on post-discharge health services utilization by comparing a set of outcome variables between intervention and non-intervention groups.
  3. Design a risk prediction model that helps identify patients discharged from in-patient care with the highest level of need for the intervention.
  4. Determine whether a community-based medication reconciliation process/intervention adds risk reduction value to individuals who have undergone an in-hospital medication reconciliation.
  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Patients attending the WestView Health Centre Medicine/Family Health Unit with at least one medication at discharge.

Exclusion Criteria:

  • First Nations persons
  • Residents of continuing care or assisted living facilities
  • Persons not residing in the Edmonton, AB, Canada region
  • Persons who obtain a score of 19 or less on the Mini Mental State Examination (MMSE)
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01164137

Locations
Canada, Alberta
WestView Health Centre
Stony Plain, Alberta, Canada, T7Z 2M7
Sponsors and Collaborators
Westview Physician Collaborative
Investigators
Principal Investigator: Allan Bailey, M.D. Westview Physician Collaborative
Study Director: Grace Moe, M.Sc.P.T. WestView Primary Care Network
  More Information

No publications provided

Responsible Party: Westview Physician Collaborative
ClinicalTrials.gov Identifier: NCT01164137     History of Changes
Other Study ID Numbers: CMPA#2026
Study First Received: July 14, 2010
Results First Received: July 19, 2012
Last Updated: February 12, 2013
Health Authority: Canada: Ethics Review Committee

Keywords provided by Westview Physician Collaborative:
Adverse Drug Events
Medication Reconciliation
Pharmacist-led Intervention

Additional relevant MeSH terms:
Drug-Related Side Effects and Adverse Reactions
Chemically-Induced Disorders

ClinicalTrials.gov processed this record on August 18, 2014