Eliminating Risk of Preventable Adverse Drug Events at the Hospital-community Interface of Care (CMR)

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Westview Physician Collaborative
ClinicalTrials.gov Identifier:
NCT01164137
First received: July 14, 2010
Last updated: February 12, 2013
Last verified: February 2013
  Purpose

This initiative aims to decrease the risk of medication errors at the hospital-community interface as well as health system utilization following hospital discharge by implementing a pharmacist-led medication reconciliation in the patients' home within 72 hours of hospital discharge.


Condition Intervention
Adverse Drug Events
Behavioral: Medication Reconciliation

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Health Services Research
Official Title: Eliminating Risk of Preventable Adverse Drug Events at the Hospital-community Interface of Care: to Develop and Test a Community-based Medication Reconciliation Program and a Risk Prediction Model That Identifies High-risk Patient Groups

Further study details as provided by Westview Physician Collaborative:

Primary Outcome Measures:
  • Health Services Utilization 3 Months Following Hospital Discharge [ Time Frame: 3 Months ] [ Designated as safety issue: Yes ]
    Mean health services utilization 3 months following hospital discharge. The specific health services utilization was re-admission to hospital, admission to home care, admission to long-term care and visits to emergency departments.

  • Health Services Utilization 6 Months Following Hospital Discharge [ Time Frame: 6 Months ] [ Designated as safety issue: Yes ]
    Mean health services utilization 6 months following hospital discharge. The specific health services utilization was re-admission to hospital, admission to home care, admission to long-term care and visits to emergency departments.

  • Health Services Utilization 9 Months Following Hospital Discharge [ Time Frame: 9 Months ] [ Designated as safety issue: Yes ]
    Mean health services utilization 9 months following hospital discharge. The specific health services utilization was re-admission to hospital, admission to home care, admission to long-term care and visits to emergency departments.

  • Health Services Utilization 12 Months Following Hospital Discharge [ Time Frame: 12 months ] [ Designated as safety issue: Yes ]
    Mean health services utilization 12 months following hospital discharge. The specific health services utilization was re-admission to hospital, admission to home care, admission to long-term care and visits to emergency departments.

  • Health Services Utilization 18 Months Following Hospital Discharge [ Time Frame: 18 months ] [ Designated as safety issue: Yes ]
    Mean health services utilization 18 months following hospital discharge. The specific health services utilization was re-admission to hospital, admission to home care, admission to long-term care and visits to emergency departments.


Enrollment: 156
Study Start Date: November 2008
Study Completion Date: February 2013
Primary Completion Date: February 2013 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Medication Reconciliation Intervention
Participants receiving a pharmacist-led home intervention conducted within 72 hours of hospital discharge aimed at identifying and correcting medication discrepancies.
Behavioral: Medication Reconciliation
A pharmacist-led home intervention conducted within 72 hours of hospital discharge aimed at correcting and identifying medication discrepancies.
No Intervention: Medication Reconciliation Non-Interven.
Participants not receiving a pharmacist-led home intervention conducted within 72 hours of hospital discharge aimed at identifying and correcting medication discrepancies.

Detailed Description:

The goals of this initiative are to decrease the risk for medication errors at the hospital community interface of care, thus decreasing preventable adverse drug events and preventable drug-related health system utilization following hospital discharge. This initiative has four objectives that aim to:

  1. Develop and test a community-based medication reconciliation process/intervention.
  2. Design and conduct a randomized controlled trial to examine the impact of the intervention on post-discharge health services utilization by comparing a set of outcome variables between intervention and non-intervention groups.
  3. Design a risk prediction model that helps identify patients discharged from in-patient care with the highest level of need for the intervention.
  4. Determine whether a community-based medication reconciliation process/intervention adds risk reduction value to individuals who have undergone an in-hospital medication reconciliation.
  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Patients attending the WestView Health Centre Medicine/Family Health Unit with at least one medication at discharge.

Exclusion Criteria:

  • First Nations persons
  • Residents of continuing care or assisted living facilities
  • Persons not residing in the Edmonton, AB, Canada region
  • Persons who obtain a score of 19 or less on the Mini Mental State Examination (MMSE)
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01164137

Locations
Canada, Alberta
WestView Health Centre
Stony Plain, Alberta, Canada, T7Z 2M7
Sponsors and Collaborators
Westview Physician Collaborative
Investigators
Principal Investigator: Allan Bailey, M.D. Westview Physician Collaborative
Study Director: Grace Moe, M.Sc.P.T. WestView Primary Care Network
  More Information

No publications provided

Responsible Party: Westview Physician Collaborative
ClinicalTrials.gov Identifier: NCT01164137     History of Changes
Other Study ID Numbers: CMPA#2026
Study First Received: July 14, 2010
Results First Received: July 19, 2012
Last Updated: February 12, 2013
Health Authority: Canada: Ethics Review Committee

Keywords provided by Westview Physician Collaborative:
Adverse Drug Events
Medication Reconciliation
Pharmacist-led Intervention

Additional relevant MeSH terms:
Drug Toxicity
Poisoning
Substance-Related Disorders

ClinicalTrials.gov processed this record on April 16, 2014