Effect of a Combined Use of Mosquito Repellent and Insecticide Treated Net on Malaria in Ethiopia

This study has been completed.
Sponsor:
Collaborators:
Addis Ababa University
Columbia University
Coalition Against Malaria in Ethiopia
Information provided by:
Malaria Consortium, Ethiopia
ClinicalTrials.gov Identifier:
NCT01160809
First received: July 8, 2010
Last updated: July 9, 2010
Last verified: July 2010
  Purpose

The combined use of a mosquito repellent and long lasting insecticidal nets (LLINs) by household members would result in a 40% reduction in malaria prevalence compared with households that only use LLINs.


Condition Intervention Phase
Malaria
Mosquito Repellent
Long Lasting Insecticidal Nets
Other: Mosquito repellent
Phase 4

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Prevention
Official Title: Effect of a Combined Use of Mosquito Repellent and Insecticide Treated Net on Malaria in Southern Ethiopia: a Cluster-randomized Controlled Trial

Resource links provided by NLM:


Further study details as provided by Malaria Consortium, Ethiopia:

Primary Outcome Measures:
  • Malaria parasite (P. falciparum and/or P. vivax)through microscopic detection [ Designated as safety issue: No ]
    The objective of the study is to investigate the impact of a combined use of mosquito repellent and LLINs in reducing malaria. The primary outcome of the study is detection of malaria parasites (P. falciparum and/or P. vivax) through examination of microscopic blood slides collected from finger-pricks.


Secondary Outcome Measures:
  • Household ownership and utilization of LLINs [ Designated as safety issue: No ]
    Owneship and utilization of LLINs by household members during the night before the baseline survey


Enrollment: 6082
Study Start Date: September 2008
Study Completion Date: January 2009
Primary Completion Date: December 2008 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Mosquito repellent and LLINs group vs. LLINs group only
This study is based on two population groups: 1) a group of households that use LLINs alone (control) and 2) a group of households that use both mosquito repellent and LLINs (repellent group).
Other: Mosquito repellent
Mosquito repellent (Buzz Off jelly) every evening applied to face, neck, hands and legs

Detailed Description:

It has been recognized that the use of malaria preventive measures in combination with LLINs could improve the effectiveness of nets in preventing the disease. This study examined the effect of a combined use of mosquito repellent (i.e., Buzz Off) and LLINs on malaria prevalence in an area of unstable and seasonal malaria transmission.

  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • All volunteer household members

Exclusion Criteria:

  • Infants less than two months
  • Not in the study area
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01160809

Locations
Ethiopia
SNNPR, Ethiopia
Awassa, Snnpr, Ethiopia
Sponsors and Collaborators
Malaria Consortium, Ethiopia
Addis Ababa University
Columbia University
Coalition Against Malaria in Ethiopia
  More Information

No publications provided

Responsible Party: Dr. Wakgari Deressa, School of Public Health, Addis Ababa University, Ethiopia
ClinicalTrials.gov Identifier: NCT01160809     History of Changes
Other Study ID Numbers: 0001
Study First Received: July 8, 2010
Last Updated: July 9, 2010
Health Authority: Ethiopia: Ministry of Ethiopian Science and Technology

Keywords provided by Malaria Consortium, Ethiopia:
Malaria
Mosquito repellent
LLINs

Additional relevant MeSH terms:
Malaria
Protozoan Infections
Parasitic Diseases

ClinicalTrials.gov processed this record on October 19, 2014