Emergency Agitation in T&A
Sevoflurane has been used commonly in pediatric anesthesia since 1990. However, it has caused more emergency agitation (EA) that other inhalation agents and the incidence is up to 80%. Therefore, lower minimum alveolar concentration of sevoflurane will reduce the EA when it is used with remifentanil in pediatric general anesthesia.
|Study Design:||Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Outcomes Assessor)
Primary Purpose: Prevention
- emergency agitation [ Time Frame: during 1 hour after recovering of anesthesia ] [ Designated as safety issue: No ]at post-anesthetic care unit
|Study Start Date:||April 2010|
|Study Completion Date:||October 2010|
|Primary Completion Date:||October 2010 (Final data collection date for primary outcome measure)|
|Active Comparator: group SR||
General anesthesia is maintained witn sevoflurane and remifentanil.
|Active Comparator: group S||
Drug: normal saline
General anesthesia is maintained with only sevoflurane and with normal saline instead of remifentanil