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Usefulness of Exhaled NO in the Differential Diagnosis Acute Eosinophilic Pneumonia and Bacterial Pneumonia

This study is ongoing, but not recruiting participants.
Sponsor:
Information provided by:
Seoul National University Bundang Hospital
ClinicalTrials.gov Identifier:
NCT01152424
First received: June 24, 2010
Last updated: June 7, 2011
Last verified: June 2011
History of Changes
  Purpose

Acute eosinophilic pneumonia (AEP) is diagnosed by cell count analysis of bronchoalveolar lavage fluid. However, the performance of bronchoscopy is not easy for patients with AEP, because they usually have hypoxia. Exhaled nitric oxide (FeNO) is usually elevated in the patients with eosinophilic inflammation such as asthma, but there is no previous studies FeNO in the patients with AEP. Investigators hypothesized that FeNO elevated significantly in patients with AEP, and FeNO can be used as non-invasive diagnostic method in patients who are clinically suspected with AEP, especially when the performance of bronchoscopy is difficult.


Condition
Acute
Eosinophilic Pneumonia

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Usefulness of Exhaled NO in the Differential Diagnosis Acute Eosinophilic Pneumonia and Community Acquired Pneumonia

Resource links provided by NLM:

MedlinePlus related topics: Pneumonia
U.S. FDA Resources

Further study details as provided by Seoul National University Bundang Hospital:

Primary Outcome Measures:
  • The difference of FeNO in AEP and Community Acquired Pneumonia [ Time Frame: Six months ] [ Designated as safety issue: No ]

Estimated Enrollment: 50
Study Start Date: July 2010
Estimated Study Completion Date: December 2011
Primary Completion Date: April 2011 (Final data collection date for primary outcome measure)
Groups/Cohorts
Acute eosinophilic pneumonia
Community acquired pneumonia

  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

All patients who visited the study hospital with bilateral pneumonic infiltration.

Criteria

Inclusion Criteria:

  • All patients who visited the study hospital with bilateral pneumonic infiltration.

Exclusion Criteria:

  • Patients who do not agree with our study protocol
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01152424

Locations
Korea, Republic of
Armed Forces Capital Hospital
Seongnam, Gyeongi, Korea, Republic of, 482 060
Sponsors and Collaborators
Seoul National University Bundang Hospital
  More Information

No publications provided by Seoul National University Bundang Hospital

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

Responsible Party: Sei Won Lee/ Assistant Professor, Seoul National University Bundang Hospital
ClinicalTrials.gov Identifier: NCT01152424     History of Changes
Other Study ID Numbers: FeNO in AEP
Study First Received: June 24, 2010
Last Updated: June 7, 2011
Health Authority: South Korea: Ministry of National Defense
South Korea: Korea Food and Drug Administration (KFDA)

Keywords provided by Seoul National University Bundang Hospital:
Acute eosinophilic pneumonia
Exhaled nitric oxide

Additional relevant MeSH terms:
Pneumonia, Bacterial
Pneumonia
Pulmonary Eosinophilia
Bacterial Infections
Lung Diseases
Respiratory Tract Diseases
 Respiratory Tract Infections
Hypereosinophilic Syndrome
Eosinophilia
Leukocyte Disorders
Hematologic Diseases

ClinicalTrials.gov processed this record on May 23, 2013