Quality of Life in Patients After Combined Modality Treatment of Rectal Cancer
The goal of this study is gathering informations about patients' quality of life after combined modality treatment of rectal cancer to evaluate how combined modality treatment for rectal cancer affects patients' quality of life. The findings of this study may provide us important information that can be used in treatment decision and to develop programs to improve quality of life of patients with rectal cancer.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Quality of Life in Patients After Combined Modality Treatment of Rectal Cancer|
- To prospectively evaluate the quality of life of patients one year after rectal cancer resection [ Time Frame: one year after the operation ] [ Designated as safety issue: No ]
- To prospectively evaluate the quality of life of patients at baseline [ Time Frame: before treatment (at baseline) ] [ Designated as safety issue: No ]consecutive patients treated winh capecitabine-based radiochemotherapy
- To prospectively evaluate the quality of life of patients two years after rectal cancer resection [ Time Frame: two years after the operation ] [ Designated as safety issue: No ]
|Study Start Date:||January 2008|
|Estimated Study Completion Date:||September 2012|
|Estimated Primary Completion Date:||September 2012 (Final data collection date for primary outcome measure)|
|rectal cancer patients||
Quality of life assessment using questionnaires EORTC QLQ C30 and 38 at baseline, one year and two years after the surgery of rectal cancer, treated with preoperative capecitabine based radiochemotherapy
Other Name: EORTC QLQ C30, EORTC QLQ C38
Over the last two decades, rectal cancer research has lead to better understanding of disease behaviour, resulting in more efficient treatments and higher prevalence of cancer survivors.Due to aggressive therapy, rectal cancer survivors can exhibit late sequelae of treatment, most common being impaired bowel, voiding, sexual malfunctioning and quality of life impairment. In order to determine the impact of rectal cancer and its treatment on patients' quality of life over time, this study will prospectively follow a cohort of patients at specified intervals evaluating their physical symptoms, physical and social functioning and overall quality of life.Medical and sociodemographic factors that might be predictive will be tested.