Prevention of MRSA Infection Among Residents of Long-term Care Homes in Canton of Vaud, Switzerland
Recruitment status was Recruiting
The purpose of this study is to determine the better approach between the currently procedure and a reinforced strategy to control and prevent infections due to MRSA in the institutionalized population of nursing homes in Canton of Vaud, Switzerland.
|Study Design:||Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Prevention
|Official Title:||Prevention of MRSA Infection Among Residents of Long-term Care Homes in Canton of Vaud, Switzerland. A Prospective, Multicenter, Interventional, Randomised Controlled Study.|
- To determine the effectiveness of the reinforced strategy compared to the standard one, to prevent MRSA transmission among residents of nursing homes [ Time Frame: 1 year ] [ Designated as safety issue: No ]general MRSA screening of all nursing homes residents of Canton Vaud at baseline and 1 year later in both group (control and intervention group)
- To determine the effectiveness of the reinforced strategy to prevent MRSA infection, compared to the standard strategy [ Time Frame: 1 year ] [ Designated as safety issue: No ]In a subpopulation of all nursing homes residents (10% of the whole population), recording of all microbiologically documented MRSA infection, according to CDC nosocomial infection definitions
- To determine MRSA prevalence among residents of nursing homes in Canton Vaud, Switzerland [ Time Frame: 1 year ] [ Designated as safety issue: No ]General MRSA screening of all nursing homes residents in Canton Vaud, Switzerland
|Study Start Date:||June 2010|
|Estimated Study Completion Date:||April 2012|
|Estimated Primary Completion Date:||December 2011 (Final data collection date for primary outcome measure)|
5 days topical decolonisation including nasal mupirocine tid, chlorexidine mouth wash tid, chlorhexidine body wash once daily.
Daily direct resident's environmental desinfection during decolonisation.
MRSA carriage among nursing homes residents of Canton Vaud, Switzerland, is increasing, despite use of standard precautions. Recommendation to prevent MRSA transmission in long term care facilities are lacking.
We aim to reinforce the current infection control strategy by general MRSA screening of institutionalised residents and decolonisation of MRSA carriers.
Because the uncertainties in the impact of this reinforced strategy, we aim to compare this action to the policy actually applied.
|Contact: Cristina Bellini, MD||+41 21 314 02 72||Cristina.Bellini@chuv.ch|
|Contact: Christiane Petignat, MD||+41 21 314 02 54||Christiane.Petignat@chuv.ch|
|all nursing homes of canton Vaud||Recruiting|
|Canton de Vaud, Canton Vaud, Switzerland|
|Contact: Christiane Petignant, MD +41 21 314 02 54 Christiane.Petignat@chuv.ch|
|Contact: Immaculée M. Nahimana, MD +41 21 314 02 55 Immaculee.Nahimana@chuv.ch|
|Principal Investigator: Cristina Bellini, MD|
|Study Director:||Giorgio Zanetti, MD||University Hospital of Lausanne, Switzerland|