Offering Proactive Tobacco Treatment

This study is currently recruiting participants.
Verified November 2012 by Masonic Cancer Center, University of Minnesota
Sponsor:
Collaborator:
Information provided by (Responsible Party):
Masonic Cancer Center, University of Minnesota
ClinicalTrials.gov Identifier:
NCT01123967
First received: May 12, 2010
Last updated: November 6, 2012
Last verified: November 2012
  Purpose

This study uses a proactive outreach strategy, coupled with free nicotine replacement therapy (NRT) to increase the population impact of tobacco cessation treatment for diverse, low income smokers. Population impact is the product of treatment utilization (i.e., reach or exposure) and treatment efficacy (i.e., smoking abstinence rates among those who utilize treatment).


Condition Intervention
Tobacco Use Cessation
Other: proactive outreach (PRO)
Other: Free telephone counseling (TC)
Other: Nicotine replacement therapy (NRT)
Other: Usual care (UC)

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Improved Effectiveness of Smoking Cessation Programs for Minnesota Priority Populations

Resource links provided by NLM:


Further study details as provided by Masonic Cancer Center, University of Minnesota:

Primary Outcome Measures:
  • Results in Abstinence Rates [ Time Frame: 1 Year ] [ Designated as safety issue: No ]
    Compare the effect of proactive outreach combined with free NRT and telephone counseling (PRO+NRT+TC) to usual care (UC) on population-level smoking abstinence rates among a diverse population of low income smokers.


Secondary Outcome Measures:
  • Results in Treatment Utilization [ Time Frame: 1 Year ] [ Designated as safety issue: No ]
    Compare the effect of proactive outreach combined with free NRT and telephone counseling (PRO+NRT+TC) to usual care (UC) on population-level tobacco treatment utilization rates among a diverse population of low income smokers.

  • Cost-Effectiveness of Program [ Time Frame: 1 Year ] [ Designated as safety issue: No ]
    Determine the cost-effectiveness of PRO+NRT+TC compared with UC.


Estimated Enrollment: 2500
Study Start Date: February 2011
Estimated Study Completion Date: January 2016
Estimated Primary Completion Date: January 2016 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: PRO+NRT+TC
Proactive outreach (mailed invitation letter followed by telephone outreach) combined with free nicotine replacement therapy (NRT) and telephone counseling (PRO+NRT+TC)to usual care (UC)
Other: proactive outreach (PRO)
a mailed invitation letter followed by telephone outreach
Other: Free telephone counseling (TC)
free telephone counseling (TC)
Other: Nicotine replacement therapy (NRT)
free nicotine replacement therapy (NRT)
Active Comparator: Usual Care (UC)
Usual (standard) care - Smoking cessation products: patch, gum, lozenge, inhaler and nasal spray
Other: Usual care (UC)
nicotine replacement products (patch, gum, lozenge, inhaler, and nasal spray)

Detailed Description:

Participants will be randomized to receive either Usual (Reactive) Care or Proactive Outreach, Telephone Counseling and free nicotine replacement therapy (NRT).

  Eligibility

Ages Eligible for Study:   18 Years to 64 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Must complete the baseline survey
  • Current self-reported cigarette smoker
  • Has a valid home address
  • An adequate proficiency in English to complete study surveys and participate in telephone counseling.
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01123967

Contacts
Contact: Steven Fu, MD 612-467-2582 fuxxx@umn.edu

Locations
United States, Minnesota
Steven Fu, M.D. Recruiting
Minneapolis, Minnesota, United States, 55417
Contact: Steven S Fu, MD     612-467-1979     Steven.Fu@va.gov    
Contact: Anne M Joseph, MD     612-626-5112     amjoseph@umn.edu    
Principal Investigator: Steven Fu, MD            
Sponsors and Collaborators
Masonic Cancer Center, University of Minnesota
Investigators
Principal Investigator: Steven Fu, M.D. Veterans Administration Hospital
Principal Investigator: Anne Joseph, MD Masonic Cancer Center, University of Minnesota
  More Information

No publications provided

Responsible Party: Masonic Cancer Center, University of Minnesota
ClinicalTrials.gov Identifier: NCT01123967     History of Changes
Other Study ID Numbers: 2009NTLS064, 0909S72235, 1R01CA141527
Study First Received: May 12, 2010
Last Updated: November 6, 2012
Health Authority: United States: Institutional Review Board

Keywords provided by Masonic Cancer Center, University of Minnesota:
nicotine replacement therapy
smoking cessation
tobacco dependent

Additional relevant MeSH terms:
Nicotine
Nicotine polacrilex
Ganglionic Stimulants
Autonomic Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs
Pharmacologic Actions
Nicotinic Agonists
Cholinergic Agonists
Cholinergic Agents
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Central Nervous System Stimulants
Central Nervous System Agents
Therapeutic Uses

ClinicalTrials.gov processed this record on May 22, 2013