Biomarkers of Metabolic Syndrome and Prediabetes

This study has been completed.
Information provided by (Responsible Party):
Kristie Bridges, West Virginia School of Osteopathic Medicine Identifier:
First received: March 11, 2010
Last updated: August 5, 2013
Last verified: August 2013

The purpose of this study is to investigate the feasibility of using salivary biomarkers to screen for complications of metabolic syndrome including prediabetes.

Metabolic Syndrome

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Cross-Sectional
Official Title: Assessing Salivary Biomarkers for Risk Stratification in Metabolic Syndrome

Resource links provided by NLM:

Further study details as provided by West Virginia School of Osteopathic Medicine:

Primary Outcome Measures:
  • Salivary Biomarker Levels [ Time Frame: baseline ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples With DNA


Enrollment: 102
Study Start Date: March 2010
Study Completion Date: December 2011
Primary Completion Date: December 2011 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   18 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

community sample


Inclusion Criteria:

  • Between the ages of 18 and 65 years
  • Males and females will be included in this study
  • All ethnic backgrounds will be included in this study
  • Acceptable health based on interview and medical history
  • Ability to comply with requirements of the study
  • Ability and willingness to provide signed informed consent

Exclusion Criteria:

  • Eating or drinking anything but water within 10 hours of sample collection
  • Autoimmune disease
  • Type 1 diabetes
  • Pregnancy (< 6 weeks postpartum)
  • History of Sjorgren's Syndrome
  • Dental work within the last two weeks
  • Ongoing or active parasitic, fungal, viral or bacterial infection
  Contacts and Locations
Please refer to this study by its identifier: NCT01086137

United States, West Virginia
West Virginia School of Osteopathic Medicine
Lewisburg, West Virginia, United States, 24901
Sponsors and Collaborators
West Virginia School of Osteopathic Medicine
Principal Investigator: Kristie G Bridges, PhD WVSOM
  More Information

No publications provided

Responsible Party: Kristie Bridges, Associate Professor, West Virginia School of Osteopathic Medicine Identifier: NCT01086137     History of Changes
Other Study ID Numbers: BCS-100.1, KB01082010
Study First Received: March 11, 2010
Last Updated: August 5, 2013
Health Authority: United States: Institutional Review Board

Keywords provided by West Virginia School of Osteopathic Medicine:
salivary biomarker
metabolic syndrome
diabetes hypertension

Additional relevant MeSH terms:
Diabetes Mellitus
Glucose Intolerance
Prediabetic State
Metabolic Syndrome X
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases
Vascular Diseases
Cardiovascular Diseases
Insulin Resistance
Hyperinsulinism processed this record on April 17, 2014