The Development of Allergic Rhinitis in Children Previously Diagnosed as Nonallergic Rhinitis
The purpose of this study is to evaluate development of allergic rhinitis in children with nonallergic rhinitis.
|Study Design:||Observational Model: Case-Only
Time Perspective: Cross-Sectional
|Official Title:||The Development of Allergic Rhinitis in Children Previously Diagnosed as Nonallergic Rhinitis|
- To evaluate the development of AR in children who were previously diagnosed with NAR [ Time Frame: 24 months ] [ Designated as safety issue: Yes ]
- To determine the persistence and severity of the symptoms, new comorbidities and triggering factors in children with nonallergic rhinitis [ Time Frame: 24 months ] [ Designated as safety issue: Yes ]
|Study Start Date:||January 2010|
|Study Completion Date:||August 2012|
|Primary Completion Date:||June 2012 (Final data collection date for primary outcome measure)|
Nonallergic rhinitis (negative skin prick test)
Procedure: skin prick test
skin prick test to aeroallergen
Other Name: SPT
Rhinitis is a common condition associated with significant effects on quality of life. Rhinitis may be divided into two groups, those with concurrent allergy (allergic rhinitis, AR) and those without allergy but who still suffer from nasal symptoms (nonallergic rhinitis, NAR).
Evidence indicated that adult with NAR can have de novo sensitization to aeroallergen (24%), suggesting that patients with NAR might evolve to AR. Thus the purpose of this study is to evaluate development of allergic rhinitis in children with nonallergic rhinitis.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01068808
|Division of Allergy and Immunology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University|
|Bangkok, Thailand, 10700|
|Principal Investigator:||Orathai Piboonpocanun, Assoc.Prof.||Division of Allergy and Immunology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand|