The Genetics of Chiari Type I Malformation
The Duke Center for Human Genetics, is investigating the hereditary basis of Chiari type I malformations with or without syringomyelia (CM1/S). Our research is aimed at learning if CM1/S is indeed caused by factors inherited through the family and, if so, which genes are involved.
Chiari Type I Malformation
|Study Design:||Observational Model: Family-Based
Time Perspective: Cross-Sectional
|Official Title:||The Genetics of Chiari Type I Malformation (CMI) With or Without Syringomyelia|
- Genetic factors contributing to Chiari Type I malformation [ Time Frame: end of study ] [ Designated as safety issue: No ]This study aims to identify genetic factors that contribute to or cause Chiari Type I malformation.
Biospecimen Retention: Samples With DNA
Whole blood, serum, DNA
|Study Start Date:||June 2009|
|Estimated Study Completion Date:||June 2014|
|Estimated Primary Completion Date:||June 2014 (Final data collection date for primary outcome measure)|
The Duke Center for Human Genetics is actively recruiting families who have TWO OR MORE family members with Chiari Type I Malformations, with or without syringomyelia. These family members must be related to each other by blood, and BOTH must be willing to participate.
|Contact: Heidi Cope, MS, CGCfirstname.lastname@example.org|
|United States, North Carolina|
|Duke University Medical Center||Recruiting|
|Durham, North Carolina, United States, 27710|
|Contact: Heidi Cope, MS, CGC 877-825-1694 email@example.com|
|Principal Investigator: Allison Ashley-Koch, PhD|
|Principal Investigator:||Allison Ashley-Koch, PhD||Duke University|