Resistant Hypertension in Patients With Type-II-Diabetes Mellitus (RESIST)
The risk of cardiovascular disease (CVD) in patients with type-II-diabetes mellitus (type-II-DM)is more than doubled and CVD accounts for 70% of deaths in this group of patients.
Hypertension is a major risk factor for CVD in patients with type-II-DM and a major contributor cardiovascular mortality. Uncontrolled- (UH) and resistant hypertension (RH)are more common in patients with type-II-DM, why further bloodpressure (BP) control is needed.
The prevalence of UH and RH has not been examined in a consecutive Danish outpatient population with type-II-DM.
The purpose of this study is to examine the prevalence of resistant hypertension in patients with type-II-diabetes and to examine the characteristics of patients with resistant hypertension as compared to patients with controlled hypertension with regards to arterial stiffness.
|Study Design:||Time Perspective: Prospective|
|Official Title:||Resistant Hypertension in Patients With Type-II-Diabetes Mellitus: Prevalence, Characterization and Treatment|
- Pulse wave velocity [ Time Frame: one year ] [ Designated as safety issue: No ]
- Myocardial contractility [ Time Frame: One year ] [ Designated as safety issue: No ]
- Pulse wave analysis [ Time Frame: One year ] [ Designated as safety issue: No ]
Biospecimen Retention: Samples Without DNA
Only serum and plasma samples are used and saved for later analysis.
|Study Start Date:||June 2009|
|Study Completion Date:||October 2011|
|Primary Completion Date:||July 2011 (Final data collection date for primary outcome measure)|
|Department of Medical Research, Svendborg Hospital|
|Svendborg, Denmark, 5700|
|Principal Investigator:||Trine K Sønder, Cand.med.||Department of Medical Research, Svendborg Hospital|