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Expression and Localization of FP Prostaglandin Receptor in Human Ocular Tissues

The recruitment status of this study is unknown because the information has not been verified recently.
Verified January 2010 by Meir Medical Center.
Recruitment status was  Not yet recruiting
Sponsor:
Information provided by:
Meir Medical Center
ClinicalTrials.gov Identifier:
NCT01054157
First received: January 21, 2010
Last updated: NA
Last verified: January 2010
History: No changes posted
  Purpose

to approve the expression of PGF2α receptors in hair follicle in ocular skin tissue, explaining the hypertrichotic effect of PG analogues as intraocular pressure lowering treatment.


Condition
Malposition of the Lower Lid

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Expression and Localization of FP Prostaglandin Receptor in Human Ocular Tissues

Further study details as provided by Meir Medical Center:

Estimated Enrollment: 50
Study Start Date: February 2010
Detailed Description:

50 hair follicle dissection - human lower lid skin and lashes will be derived from lateral tarsal strip (LTS) dissected routinely in ectropion repair surgery, the skin strip is dissected routinely in this surgery , without any relation to our study. The study will be planned according to Helsinki declaration for Paraffin embedded LTS tissue sections (4 µ) will be processed and examined in immunohistochemistry lab. FP receptor proteins expression, using subtype-specific polyclonal antibodies, will be detected by the light microscopic level, according to manufacturer instruction.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

human lower lid skin and lashes will be derived from lateral tarsal strip (LTS) dissected routinely in ectropion repair surgery, the skin strip is dissected routinely in this surgery

Criteria

Inclusion Criteria:

  • age > 18 years
  • malposition of lower eyelid

Exclusion Criteria:

  • age < 18 years
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01054157

Sponsors and Collaborators
Meir Medical Center
Investigators
Principal Investigator: halah el naddaf, doctor Meir Medical Center
  More Information

No publications provided

Responsible Party: halah el naddaf, meir medical center
ClinicalTrials.gov Identifier: NCT01054157     History of Changes
Other Study ID Numbers: PROST-1
Study First Received: January 21, 2010
Last Updated: January 21, 2010
Health Authority: Israel: Ethics Commission

ClinicalTrials.gov processed this record on May 19, 2013