Study of Integrity of Down Inhibitor Bundle at Patients Suffering of Neuropathic Pain (PhyDoNe)

This study has been completed.
Sponsor:
Collaborator:
Grünenthal GmbH
Information provided by (Responsible Party):
University Hospital, Clermont-Ferrand
ClinicalTrials.gov Identifier:
NCT01053845
First received: January 19, 2010
Last updated: July 4, 2014
Last verified: July 2014
  Purpose

Several studies showed that activity of down inhibitor bundle is weakened in different painful pathologies as the fibromyalgy or the trigeminal nevralgy.

The purpose of the protocol is to study the working of down inhibitor bundle at patients suffering of neuropathic pain.


Condition Intervention Phase
Healthy Volunteers
Patients Suffering of Peripheral Neuropathic Pain
Other: Neuropathic pain
Phase 1

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Diagnostic
Official Title: Study of Integrity of Down Inhibitor Bundle at Patients Suffering of Neuropathic Pain

Further study details as provided by University Hospital, Clermont-Ferrand:

Primary Outcome Measures:
  • Comparison of the amplitude of N2P2 waves between healthy volunteers and patients suffering of peripheral neuropathic pain. [ Designated as safety issue: Yes ]

Enrollment: 20
Study Start Date: April 2010
Study Completion Date: May 2011
Primary Completion Date: May 2011 (Final data collection date for primary outcome measure)
Intervention Details:
    Other: Neuropathic pain
    to study the working of down inhibitor bundle at patients suffering of neuropathic pain
Detailed Description:

Prospective study with comparison groups

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • neuropathic patients group

    • Patient suffering of peripheral neuropathic pain
    • 18 years old women or men at least

Exclusion Criteria:

  • • Healthy volunteers

    • 18 years old women or men at least
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01053845

Locations
France
Chu Clermont-Ferrand
Clermont-Ferrand, France, 63003
Sponsors and Collaborators
University Hospital, Clermont-Ferrand
Grünenthal GmbH
Investigators
Principal Investigator: Gisèle Pickering, Dr University Hospital, Clermont-Ferrand
  More Information

No publications provided

Responsible Party: University Hospital, Clermont-Ferrand
ClinicalTrials.gov Identifier: NCT01053845     History of Changes
Other Study ID Numbers: CHU-0066, 2009-A00155-52
Study First Received: January 19, 2010
Last Updated: July 4, 2014
Health Authority: France: Ministry of Health

Keywords provided by University Hospital, Clermont-Ferrand:
Neuropathic pain

Additional relevant MeSH terms:
Neuralgia
Stress, Psychological
Pain
Neurologic Manifestations
Nervous System Diseases
Peripheral Nervous System Diseases
Neuromuscular Diseases
Signs and Symptoms
Behavioral Symptoms

ClinicalTrials.gov processed this record on August 28, 2014