Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma

This study is currently recruiting participants. (see Contacts and Locations)
Verified June 2014 by Stanford University
Sponsor:
Collaborator:
Information provided by (Responsible Party):
Stanford University
ClinicalTrials.gov Identifier:
NCT01048281
First received: January 11, 2010
Last updated: June 27, 2014
Last verified: June 2014
  Purpose

Our research of the biology of upper gastrointestinal cancers involves the study of tissue samples and cells from biopsies of persons with gastric or esophageal cancer or blood samples from upper gastrointestinal cancer patients and persons at high inherited risk for these cancers. We hope to learn the role genes and proteins play in the development of gastric and esophageal cancer.


Condition Intervention
Stomach Cancer
Gastro-Esophageal(GE) Junction Cancer
Gastric (Stomach) Cancer
Esophageal Cancer
Gastrointestinal Stromal Tumor (GIST)
Procedure: Blood draw
Procedure: Tissue tumor biopsy

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma

Resource links provided by NLM:


Further study details as provided by Stanford University:

Primary Outcome Measures:
  • p53 activity by routine pathologic analysis [ Time Frame: time of collection ] [ Designated as safety issue: No ]
  • NER activity by routine pathologic analysis [ Time Frame: time of collection ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples With DNA

blood, tumor


Estimated Enrollment: 100
Study Start Date: August 2002
Estimated Study Completion Date: December 2015
Estimated Primary Completion Date: December 2015 (Final data collection date for primary outcome measure)
  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Adults with gastric or esophageal cancer

Criteria

Inclusion Criteria:1. Over 18 2. Diagnosed with gastric or esophageal cancer OR at an increased hereditary risk for upper GI cancer

Exclusion Criteria:1. Under 18 2. No family or personal history of gastric or esophageal cancer

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01048281

Contacts
Contact: Meredith Mills (650) 724-5223 bluett@stanford.edu

Locations
United States, California
Stanford University School of Medicine Recruiting
Stanford, California, United States, 94305
Contact: Meredith Mills    650-724-5223    bluett@stanford.edu   
Principal Investigator: James M Ford         
Sub-Investigator: Hanlee P. Ji         
Sub-Investigator: Vandana Bhardwaj Sharma         
Sponsors and Collaborators
Stanford University
Investigators
Principal Investigator: James M Ford Stanford University
  More Information

No publications provided

Responsible Party: Stanford University
ClinicalTrials.gov Identifier: NCT01048281     History of Changes
Other Study ID Numbers: GIUPR0001, 76274, CA109190, SU-11022007-787
Study First Received: January 11, 2010
Last Updated: June 27, 2014
Health Authority: United States: Institutional Review Board

Additional relevant MeSH terms:
Carcinoma
Esophageal Neoplasms
Stomach Neoplasms
Rectal Neoplasms
Pancreatic Neoplasms
Duodenal Neoplasms
Bile Duct Neoplasms
Gastrointestinal Stromal Tumors
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type
Neoplasms
Gastrointestinal Neoplasms
Digestive System Neoplasms
Neoplasms by Site
Head and Neck Neoplasms
Digestive System Diseases
Esophageal Diseases
Gastrointestinal Diseases
Stomach Diseases
Colorectal Neoplasms
Intestinal Neoplasms
Intestinal Diseases
Rectal Diseases
Endocrine Gland Neoplasms
Pancreatic Diseases
Endocrine System Diseases
Duodenal Diseases
Biliary Tract Neoplasms
Bile Duct Diseases
Biliary Tract Diseases

ClinicalTrials.gov processed this record on July 24, 2014