Multicenter Cross Sectional Study of Primary Intestine Lymphoma
The purpose of this study is to determine whether whether surgical resection followed by chemotherapy is superior to systemic chemotherapy alone in terms of treatment outcome and quality of life (QOL) in patients with primary intestinal lymphoma.
Non-Hodgkin Lymphoma of Intestine
|Study Design:||Observational Model: Case Control
Time Perspective: Cross-Sectional
|Official Title:||Multicenter Cross Sectional Study of Primary Intestine Lymphoma: Treatment Outcome and Quality of Life|
- Overall survival [ Time Frame: Study entry ] [ Designated as safety issue: No ]
- Quality of life [ Time Frame: Study entry ] [ Designated as safety issue: No ]
|Study Start Date:||September 2008|
|Study Completion Date:||March 2010|
|Primary Completion Date:||March 2010 (Final data collection date for primary outcome measure)|
Primary mass was resected and systemic chemotherapy was performed as an adjuvant treatment
Only treated with chemotherapy
Intestine is the one of commonly involved extranodal sites of non-Hodgkin's lymphoma (NHL). Thus, small and large Intestine account for approximately 30-40% of primary gastrointestinal tract lymphoma. More than 70% of intestinal lymphoma presents as localized disease, and surgery such as bowel resection is performed in many patients with intestinal lymphoma for diagnosis and treatment. However, it is still unclear whether surgical resection followed by chemotherapy is superior to systemic chemotherapy alone in terms of treatment outcome and quality of life (QOL). Thus, we analyze the clinical features and treatment outcome of patients with NHL of intestine, and at the same time perform a multicenter cross-sectional study about the QOL in survivors of intestine NHL. We evaluates the treatment outcomes of patients with intestine NHL from hospitals affiliated with the Consortium for Improving Survival of Lymphoma (CISL) in Korea. We assess the QOL of survivors who completed their treatment using the EORTC QLQ-C30 questionnaire.