Sexually Transmitted Infections Among African American Women Who Have Sex With Women (WSW)

This study has suspended participant recruitment.
Sponsor:
Collaborator:
Mississippi State Department of Health
Information provided by:
University of Mississippi Medical Center
ClinicalTrials.gov Identifier:
NCT01043081
First received: January 4, 2010
Last updated: April 2, 2012
Last verified: July 2010
  Purpose

The purpose of this study is to determine the rates of sexually transmitted infections (STI) among a group of African American women who have sex with women (AA WSW). The first study hypothesis is that AA WSW are at risk for acquiring and transmitting STI, including the human immunodeficiency virus (HIV). The second study hypothesis is that AA WSW participate in multiple high-risk sexual activities that may facilitate transmission of STIs, including HIV.


Condition
Sexually Transmitted Infections
HIV Infections

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Cross-Sectional
Official Title: Prevalence Rates of Sexually Transmitted Infections and Sexual Risk Behaviors Among African American Women Who Have Sex With Women

Resource links provided by NLM:


Further study details as provided by University of Mississippi Medical Center:

Primary Outcome Measures:
  • Prevalence rates of sexually transmitted infections [ Time Frame: 18 Months ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Associated sexual risk behaviors [ Time Frame: 18 Months ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples With DNA

Endocervical and vaginal secretion specimens are being retained for future research studies in this field of sexually transmitted diseases.


Estimated Enrollment: 300
Study Start Date: February 2009
Estimated Study Completion Date: June 2012
Primary Completion Date: December 2011 (Final data collection date for primary outcome measure)
Detailed Description:

Historically, women who have sex with women (WSW) have been thought to be at low risk for acquiring sexually transmitted infections (STI), presumably due to the absence of genital mucosal contact present during vaginal-penile sex or due to the assumption that the vaginal mucosa experiences a lesser degree of trauma during female sex than during heterosexual sex. This assumption has been challenged and debated over the past two decades. In addition, the sexual health risks of WSW are only beginning to be understood.

To date the majority of research regarding STI in women has occurred in heterosexuals. National and local surveillance data that estimate the risk for STI transmission between WSW are limited, especially among African Americans. This is a group of women that may exhibit distinctive behavioral characteristics that may put them at higher risk for sexually transmitted infections STI and HIV than their Caucasian counterparts. This group of women has traditionally been reluctant to discuss their sexual orientation with physicians for fear of being stigmatized. The burden of STIs, including HIV, experienced by this group of women is largely unknown.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

The study population is African American women, aged 18 or above, who present to the Crossroads Clinic (STD Clinic) in the Jackson, MS metropolitan area for STI screening/evaluation who have engaged in sexual contact with another woman within the past 6 months.

Criteria

Inclusion Criteria:

  • Female
  • Age 18 years or older
  • African American race
  • Sexual contact with another female within the past 6 months
  • Ability to give written informed consent

Exclusion Criteria:

  • Male
  • Age less than 18 years old
  • Race other than African American
  • No sexual contact with another woman within the past 6 months
  • Pregnant
  • Prior enrollment in this study
  • Participants who, for any reason, in the opinion of the investigator, do not have the ability to give written informed consent or may not be expected to comply with the requirements of the protocol
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01043081

Locations
United States, Mississippi
Crossroads Clinic
Jackson, Mississippi, United States, 39216
Sponsors and Collaborators
University of Mississippi Medical Center
Mississippi State Department of Health
Investigators
Principal Investigator: Leandro A Mena, MD, MPH University of Mississippi Medical Center
  More Information

No publications provided by University of Mississippi Medical Center

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Leandro Mena, M.D., University of Mississippi Medical Center, Division of Infectious Diseases
ClinicalTrials.gov Identifier: NCT01043081     History of Changes
Other Study ID Numbers: 2008-0143
Study First Received: January 4, 2010
Last Updated: April 2, 2012
Health Authority: United States: Institutional Review Board

Keywords provided by University of Mississippi Medical Center:
African American women who have sex with women
Sexually transmitted infections
Homosexuality
Human papillomavirus
Cervical intraepithelial neoplasia
Herpes simplex virus types 1 and 2
Chlamydia
Gonorrhea
Trichomoniasis
Bacterial vaginosis
Syphilis
Human immunodeficiency virus

Additional relevant MeSH terms:
Genital Diseases, Female
HIV Infections
Acquired Immunodeficiency Syndrome
Sexually Transmitted Diseases
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Virus Diseases
Sexually Transmitted Diseases, Viral
Immunologic Deficiency Syndromes
Immune System Diseases
Slow Virus Diseases
Infection
Genital Diseases, Male

ClinicalTrials.gov processed this record on August 26, 2014