Attempts to Stop/Reduce Marijuana Among Dependent Users

This study has been completed.
Sponsor:
Collaborator:
Information provided by (Responsible Party):
John Hughes, University of Vermont
ClinicalTrials.gov Identifier:
NCT01039415
First received: December 24, 2009
Last updated: September 17, 2013
Last verified: September 2013
  Purpose

The purpose of the study is to determine why and how marijuana users stop or reduce their marijuana use.


Condition
Marijuana Abuse
Marijuana Dependence

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Attempts to Stop/Reduce Marijuana Among Dependent Users

Resource links provided by NLM:


Further study details as provided by University of Vermont:

Primary Outcome Measures:
  • initiation of a quit or reduction attempt [ Time Frame: during 3 months of monitoring ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • duration of a quit attempt [ Time Frame: during the 3 months of monitoring ] [ Designated as safety issue: No ]

Enrollment: 234
Study Start Date: June 2010
Study Completion Date: October 2012
Primary Completion Date: October 2012 (Final data collection date for primary outcome measure)
Detailed Description:

The major aim of this study is to provide a better understanding of attempts to stop or reduce marijuana use that can be used to develop better behavioral treatments for marijuana dependence. The application will focus on adult daily marijuana users who try to stop or reduce their marijuana use in a real-world setting. Although prospective, natural history studies describing attempts to stop or reduce alcohol, heroin and tobacco use have proved useful, we know of no such study among adult marijuana users. Two pilot studies will develop measures and assess compliance with our procedures. The main study will recruit up to 400 adult marijuana smokers with the goal of a sample size of 200 participants with adequate compliance. Participants will call an Interactive Voice Recording (IVR) system daily for 3 months to report marijuana use, quit/reduction attempts, and events that might increase or decrease the probability of initiating a quit/reduction attempt or the success of an attempt. Follow-up at 6 months will track recent marijuana and other drug use. Knowing what motivates marijuana users to try to stop or reduce, and knowing which strategies for stopping marijuana use are successful, can help develop treatments for marijuana dependence. For example, if stopping tobacco when trying to stop marijuana decreases the chance of stopping marijuana, then smoking cessation should be done after stopping marijuana. Or if reducing marijuana often leads to cessation, then convincing those not interested in quitting marijuana to first try reducing may be helpful.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

adults 18 and older

Criteria

Inclusion Criteria:

  • daily marijuana smokers for at least 1 year

Exclusion Criteria:

  • pregnant women
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01039415

Locations
United States, Vermont
University of Vermont
Burlington, Vermont, United States, 05401
Sponsors and Collaborators
University of Vermont
Investigators
Principal Investigator: John Hughes, MD University of Vermont
  More Information

No publications provided

Responsible Party: John Hughes, Professor of psychiatry, University of Vermont
ClinicalTrials.gov Identifier: NCT01039415     History of Changes
Other Study ID Numbers: CHRBS #09-005, R01DA024691
Study First Received: December 24, 2009
Last Updated: September 17, 2013
Health Authority: United States: Institutional Review Board

Keywords provided by University of Vermont:
marijuana
marijuana abuse
marijuana dependence
cannabis
substance-related disorder
abstinence

Additional relevant MeSH terms:
Marijuana Abuse
Substance-Related Disorders
Chemically-Induced Disorders
Mental Disorders

ClinicalTrials.gov processed this record on September 16, 2014