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Epstein-Barr Detection in Oral Cancer

The recruitment status of this study is unknown because the information has not been verified recently.
Verified December 2009 by UPECLIN HC FM Botucatu Unesp.
Recruitment status was  Active, not recruiting
Sponsor:
Information provided by:
UPECLIN HC FM Botucatu Unesp
ClinicalTrials.gov Identifier:
NCT01039272
First received: December 22, 2009
Last updated: NA
Last verified: December 2009
History: No changes posted
  Purpose

The aim of this study is to analyze oral squamous cell carcinoma and healthy oral mucosa for the possible presence of Epstein-Barr virus (EBV).


Condition
Oral Cancer

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Cross-Sectional
Official Title: Epstein-Barr Detection in Squamous Cell Carcinoma and Healthy Oral Mucosa

Resource links provided by NLM:


Further study details as provided by UPECLIN HC FM Botucatu Unesp:

Biospecimen Retention:   Samples With DNA

paraffin-embedded tissue samples


Enrollment: 60
Study Start Date: March 2008
Estimated Study Completion Date: March 2010
Primary Completion Date: November 2009 (Final data collection date for primary outcome measure)
Groups/Cohorts
oral cancer
patients with oral squamous cell carcinoma
control group
healthy patients without any oral pathology

Detailed Description:

Epstein-Barr virus has been implicated in a range of malignant neoplasms, including in some studies, in the aetiology of oral squamous cell carcinoma but the influence of EBV in oral cancer remains unclear. This study will examine the prevalence of EBV infection in oral cancer by means of nested polymerase chain reaction.

  Eligibility

Ages Eligible for Study:   40 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

oral care clinic, community sample

Criteria

Inclusion Criteria:

  • patients of Oral Cancer Centre - UNESP/Araçatuba - SP
  • with oral squamous cell carcinoma

Exclusion Criteria:

  • without oral squamous cell carcinoma
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01039272

Locations
Brazil
Department of Pathology and Propaedeutics, Sao Paulo State University, Unesp, Araçatuba/SP
Araçatuba, São Paulo, Brazil, 16025-050
Sponsors and Collaborators
UPECLIN HC FM Botucatu Unesp
Investigators
Principal Investigator: Glauco Issamu I Miyahara, Professor Department of Pathology and Propaedeutics, Sao Paulo State University, Unesp, Araçatuba/SP
Study Chair: Lívia T Arêde, student Department of Pathology and Propaedeutics, Sao Paulo State University, Unesp, Araçatuba/SP
  More Information

No publications provided

Responsible Party: Glauco Issamu Miyahara/ Professor, School of Dentistry, Sao Paulo State University, Unesp, Araçatuba/SP
ClinicalTrials.gov Identifier: NCT01039272     History of Changes
Other Study ID Numbers: upeclin/FOA-Unesp-03
Study First Received: December 22, 2009
Last Updated: December 22, 2009
Health Authority: Brazil: National Committee of Ethics in Research

Keywords provided by UPECLIN HC FM Botucatu Unesp:
oral cancer
EBV
PCR

Additional relevant MeSH terms:
Mouth Neoplasms
Head and Neck Neoplasms
Mouth Diseases
Neoplasms
Neoplasms by Site
Stomatognathic Diseases

ClinicalTrials.gov processed this record on November 19, 2014