Chronic Alcohol and Brain Stress Circuit Response

This study is currently recruiting participants.

Verified February 2011 by Yale University

First Received on December 10, 2009. Last Updated on February 4, 2011 History of Changes

Sponsor:	Yale University
Collaborator:	National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Information provided by:	Yale University
ClinicalTrials.gov Identifier:	NCT01031264

Purpose

Alcoholism is among the top three causes of preventable death and disease in the US (Mokdad et al., 2004; Room et al., 2005). Stress plays an important role in the development of alcoholism and in high vulnerability to alcohol relapse. This study will provide a greater understanding of the mechanism by which stress and alcohol consumption interacts to influence development of compulsive alcohol seeking and vulnerability to stress-induced drinking, and the results will have significant implications for the development of new prevention and treatment interventions for alcoholism.

Condition
Stress Alcoholism

Study Type:	Observational
Study Design:	Observational Model: Cohort Time Perspective: Prospective
Official Title:	Chronic Alcohol and Brain Stress Circuit Response

Resource links provided by NLM:

MedlinePlus related topics: Alcoholism

U.S. FDA Resources

Further study details as provided by Yale University:

Estimated Enrollment:	120
Study Start Date:	January 2009
Estimated Primary Completion Date:	December 2014 (Final data collection date for primary outcome measure)

Groups/Cohorts
Social drinkers

Eligibility

Ages Eligible for Study:	21 Years to 50 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes
Sampling Method:	Non-Probability Sample

Study Population

social drinkers

Criteria

Inclusion Criteria:

ages 21-50

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT01031264

Locations

United States, Connecticut
Yale Stress Center	Recruiting
New Haven, Connecticut, United States, 06519
Contact: Keri L Tuit, Psy.D. 203-737-1176 keri.tuit@yale.edu
Principal Investigator: Rajita Sinha, PhD

Sponsors and Collaborators

Yale University

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Investigators

Principal Investigator:

Rajita Sinha, PhD

Yale University

More Information

No publications provided

Responsible Party:	Rajita Sinha, PhD., Yale University
ClinicalTrials.gov Identifier:	NCT01031264 History of Changes
Other Study ID Numbers:	0706002821, R01AA013892
Study First Received:	December 10, 2009
Last Updated:	February 4, 2011
Health Authority:	United States: Institutional Review Board

Keywords provided by Yale University:

social drinkers

Additional relevant MeSH terms:

Alcoholism
Alcohol-Related Disorders
Substance-Related Disorders
Mental Disorders

ClinicalTrials.gov processed this record on May 23, 2012