Isovolumetric and Isocaloric Preloads of Various Types of Milk on Food Intake, Subjective Appetite and Glycemic Response

This study has been completed.
Sponsor:
Collaborators:
Dairy Farmers of Ontario
Mondelēz International, Inc.
Natural Sciences and Engineering Research Council, Canada
Information provided by (Responsible Party):
G. Harvey Anderson, University of Toronto
ClinicalTrials.gov Identifier:
NCT01025557
First received: December 2, 2009
Last updated: June 13, 2012
Last verified: June 2012
  Purpose

The purpose of this protocol is to study the effects of fluid milk products on satiety, food intake, and glucose metabolism in healthy young men and women. Experiment 1: The specific objective is to investigate isovolumetric amounts of milk (2% M.F.), chocolate milk (1% M.F.), a soy beverage, cow's milk-based infant formula, and water (control) on satiety and food intake and on blood glucose before and after a meal. A fixed volume approach is based on the commercially available serving size. Experiment 2 will examine equicaloric amounts of milk (2% M.F.), chocolate milk (1% M.F.), a soy beverage, cow's milk-based infant formula, a glucose drink and water (control) the treatments in order to investigate macronutrient composition on satiety and food intake and on blood glucose before and after the meal.


Condition Intervention Phase
Diabetes Prevention
Obesity Prevention
Other: Dietary intervention
Phase 1
Phase 2

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Crossover Assignment
Masking: Single Blind (Investigator)
Primary Purpose: Basic Science
Official Title: The Effects of Isovolumetric and Isocaloric Preloads of Various Types of Milk on Food Intake, Subjective Appetite and Glycemic Response in Healthy Young Men and Women

Resource links provided by NLM:


Further study details as provided by University of Toronto:

Primary Outcome Measures:
  • Food intake [ Time Frame: 30 minute ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Blood glucose [ Time Frame: 0, 10, 20, 30, 50, 80, 110, 140 and 170 minutes ] [ Designated as safety issue: No ]

Enrollment: 52
Study Start Date: September 2009
Study Completion Date: May 2012
Primary Completion Date: June 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Chocolate milk Other: Dietary intervention
Dietary treatments with beverages
Experimental: Milk Other: Dietary intervention
Dietary treatments with beverages
Experimental: Infant formula Other: Dietary intervention
Dietary treatments with beverages
Experimental: Soy beverage Other: Dietary intervention
Dietary treatments with beverages
Experimental: Water Other: Dietary intervention
Dietary treatments with beverages

  Eligibility

Ages Eligible for Study:   20 Years to 30 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Healthy
  • Non-smoking
  • Aged 20-30 years
  • Body mass index between 20 and 24.9 kg/m2

Exclusion Criteria:

  • Diabetes
  • Medication
  • Lactose-intolerance or allergies to milk
  • Breakfast skippers and those on an energy restricted diet
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01025557

Locations
Canada, Ontario
University of Toronto
Toronto, Ontario, Canada, M5S 3E2
Sponsors and Collaborators
University of Toronto
Dairy Farmers of Ontario
Mondelēz International, Inc.
Natural Sciences and Engineering Research Council, Canada
Investigators
Principal Investigator: Harvey Anderson, Ph.D. University of Toronto
  More Information

No publications provided

Responsible Party: G. Harvey Anderson, Professor, University of Toronto
ClinicalTrials.gov Identifier: NCT01025557     History of Changes
Other Study ID Numbers: Milk Study - Experiment 1, DFO_24235
Study First Received: December 2, 2009
Last Updated: June 13, 2012
Health Authority: Canada: Health Canada

Keywords provided by University of Toronto:
Food intake
Blood glucose
Milk

ClinicalTrials.gov processed this record on October 19, 2014