Effects of Inulin on Satiety and Food Intake
To assess the effect of inulin on appetite profile ratings, food intake and satiety hormones.
|Study Design:||Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Double Blind (Subject, Investigator)
|Official Title:||Effects of Inulin on Satiety and Food Intake|
- food intake [ Time Frame: on testday 0 and 13 ] [ Designated as safety issue: No ]
- appetite profile ratings [ Time Frame: on test day 0, 8 and 13 (at 16 time points) ] [ Designated as safety issue: No ]
- satiety hormones (GLP-1 and PYY) [ Time Frame: on test day 0 and 13 (at 9 time points ] [ Designated as safety issue: No ]
|Study Start Date:||January 2009|
|Study Completion Date:||February 2010|
|Primary Completion Date:||February 2010 (Final data collection date for primary outcome measure)|
Dietary Supplement: inulin
Based upon a slower digestion and the fermentation in the intestinal tract, food containing soluble dietary fibres, such as inulin, is hypothesized to be more satiating, and to limit energy intake, in humans. Does supplementation of inulin (at 2 dosages) versus placebo over 13 consecutive days in normal to overweight men and women, lead to an increase in satiety, a reduction in food intake and stronger postprandial increases in GLP-1 and PYY?