Different Metabolic Effects of Statins

This study has been completed.
Sponsor:
Information provided by:
Gachon University Gil Medical Center
ClinicalTrials.gov Identifier:
NCT01011127
First received: November 10, 2009
Last updated: October 4, 2010
Last verified: October 2010
  Purpose

The investigators hypothesize that pravastatin and rosuvastatin may have different metabolic effects in hypercholesterolemic patients.


Condition Intervention
Hypercholesterolemia
Drug: pravastatin, rosuvastatin

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective

Resource links provided by NLM:


Further study details as provided by Gachon University Gil Medical Center:

Study Start Date: December 2009
Study Completion Date: August 2010
Primary Completion Date: July 2010 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
pravastatin Drug: pravastatin, rosuvastatin
rosuvastatin Drug: pravastatin, rosuvastatin

  Eligibility

Ages Eligible for Study:   25 Years to 75 Years
Genders Eligible for Study:   Both
Sampling Method:   Probability Sample
Study Population

Hypercholesterolemia

Criteria

Inclusion Criteria:

  • Low-density lipoprotein cholesterol levels>130

Exclusion Criteria:

  • Overt liver disease Chronic renal failure Hypothyroidism Myopathy Uncontrolled diabetes Severe hypertension
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01011127

Locations
Korea, Republic of
Gil Medical Center
Incheon, Korea, Republic of, 405-760
Sponsors and Collaborators
Gachon University Gil Medical Center
  More Information

Publications:
ClinicalTrials.gov Identifier: NCT01011127     History of Changes
Other Study ID Numbers: GMC-200914
Study First Received: November 10, 2009
Last Updated: October 4, 2010
Health Authority: South Korea: Institutional Review Board

Keywords provided by Gachon University Gil Medical Center:
Statins
Insulin resistance

Additional relevant MeSH terms:
Hypercholesterolemia
Hyperlipidemias
Dyslipidemias
Lipid Metabolism Disorders
Metabolic Diseases
Pravastatin
Rosuvastatin
Anticholesteremic Agents
Hypolipidemic Agents
Antimetabolites
Molecular Mechanisms of Pharmacological Action
Pharmacologic Actions
Lipid Regulating Agents
Therapeutic Uses
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Enzyme Inhibitors

ClinicalTrials.gov processed this record on September 30, 2014