C-Reactive Protein as a Predictor for Airway Hyper-Responsiveness

This study has been completed.
Information provided by:
Rambam Health Care Campus
ClinicalTrials.gov Identifier:
First received: September 30, 2009
Last updated: October 26, 2009
Last verified: October 2009

Background: Increased serum high sensitivity C-reactive protein (hs-CRP) has been associated with airway inflammation in asthma and may serve as a surrogate marker for the presence of airway hyper-responsiveness (AHR) in this set-up. This study was designed to evaluate the predictive value of hs-CRP for AHR assessed by metacholine challenge test (MCT), in adults with suspected Asthma.

Condition Intervention
Other: blood sampling

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: C-Reactive Protein as a Predictor for Airway Hyper-responsiveness

Resource links provided by NLM:

Further study details as provided by Rambam Health Care Campus:

Enrollment: 88
Study Start Date: March 2007
Study Completion Date: May 2009
Primary Completion Date: March 2009 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

people with suspected asthma underwent metacholine chalange test.


Inclusion Criteria:

  • subjects that were referred to Metacholine challenge test

Exclusion Criteria:

  • age < 18
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01002144

Sponsors and Collaborators
Rambam Health Care Campus
Principal Investigator: Mordechai Yigla, MD Rambam Health Care Campus
  More Information

No publications provided

Responsible Party: the sponsor is the principal investigator, Rambam Health Care Campus
ClinicalTrials.gov Identifier: NCT01002144     History of Changes
Other Study ID Numbers: CRPAHR - CTIL
Study First Received: September 30, 2009
Last Updated: October 26, 2009
Health Authority: Israel: Ministry of Health

Additional relevant MeSH terms:
Bronchial Diseases
Respiratory Tract Diseases
Lung Diseases, Obstructive
Lung Diseases
Respiratory Hypersensitivity
Hypersensitivity, Immediate
Immune System Diseases

ClinicalTrials.gov processed this record on April 15, 2014