Individual Differences in Diabetes Risk: Role of Slow WaveSleep

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
University of Chicago
ClinicalTrials.gov Identifier:
NCT00989378
First received: October 1, 2009
Last updated: September 4, 2013
Last verified: September 2013
  Purpose

This study will examine the relationship between the amount of slow wave sleep (deep sleep) and the ability of the body to bring the blood sugar level to a normal range after receiving glucose.


Condition Intervention
Sleep
Diabetes
Behavioral: baseline study

Study Type: Observational
Study Design: Observational Model: Cohort
Official Title: Ancillary Studies to Major Ongoing NIDDK Clinical Research Studies

Resource links provided by NLM:


Further study details as provided by University of Chicago:

Primary Outcome Measures:
  • Amount of Slow Wave Activity determines insulin sensitivity. [ Time Frame: 2 days ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples Without DNA

serum


Enrollment: 5
Study Start Date: November 2008
Study Completion Date: September 2010
Primary Completion Date: September 2010 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
control
normal healthy men and women
Behavioral: baseline study
normal bedtimes

  Eligibility

Ages Eligible for Study:   18 Years to 20 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

normal healthy men and women

Criteria

Inclusion Criteria:

  • healthy volunteers age 18-20 with a BMI < 27kg/m2 in women and < 28 kg/m2 in men with normal findings on clinical examination, routine laboratory tests and EKG
  • only subjects who have regular life styles (no shift work, no travel across time zone during the previous 4 weeks)
  • habitual bedtimes between 7.0-8.5 hours/night
  • do not take medications will be recruited

Exclusion Criteria:

  • women taking hormonal contraceptive therapy and pregnant women will be excluded
  • individuals with a history of psychiatric, endocrine, cardiac or sleep disorders will be excluded
  • other exclusion criteria will be: tobacco use, habitual alcohol use of more than 1 drink per day, excessive caffeine intake of more than 300 mg per day
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00989378

Locations
United States, Illinois
University of Chicago
Chicago, Illinois, United States, 60637
Sponsors and Collaborators
University of Chicago
Investigators
Principal Investigator: Eve Van Cauter, Ph.D. University of Chicago
  More Information

No publications provided

Responsible Party: University of Chicago
ClinicalTrials.gov Identifier: NCT00989378     History of Changes
Other Study ID Numbers: 16026A
Study First Received: October 1, 2009
Last Updated: September 4, 2013
Health Authority: United States: Institutional Review Board

Keywords provided by University of Chicago:
sleep
insulin
diabetes
determine association between sleep characteristics and diabetes risk

Additional relevant MeSH terms:
Diabetes Mellitus
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases

ClinicalTrials.gov processed this record on September 22, 2014