Effects of Sleep Deprivation on Food Intake and Motor Activity in Man

This study has been completed.
Sponsor:
Collaborator:
Centre Hospitalier Universitaire Dijon
Information provided by:
University Hospital, Caen
ClinicalTrials.gov Identifier:
NCT00986492
First received: September 24, 2009
Last updated: September 29, 2009
Last verified: September 2009
  Purpose

Evidence that shortened period of sleep could be a risk factor for weight gain and obesity has grown over the past decade. Concurrent with the obesity epidemic, numerous studies have reported a parallel epidemic of chronic sleep deprivation. Sleep is important in maintaining energy balance (i.e. acute sleep deprivation impact the normal secretion of ghrelin and decreases leptin plasma levels). Surprisingly, in humans, there is no direct evidence that a shortened night has direct effect on energy metabolism during the following day.

This study is set up to determine whether a partial sleep deprivation night has an impact on appetite and food energy intake and, concomitantly, on physical activity, during the following day.


Condition
Healthy

Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: Influence de la Privation Aigue de Sommeil Sur la Prise Alimentaire et l'activité Physique Chez l'Homme

Further study details as provided by University Hospital, Caen:

Primary Outcome Measures:
  • Daily food intake [ Time Frame: 24h ] [ Designated as safety issue: No ]

Enrollment: 12
Study Start Date: April 2009
Study Completion Date: June 2009
Primary Completion Date: June 2009 (Final data collection date for primary outcome measure)
  Eligibility

Ages Eligible for Study:   18 Years to 30 Years
Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Healthy normal subjects

Criteria

Inclusion Criteria:

  • male
  • age between 18 and 30
  • healthy
  • non smoker
  • less than 5 hour of sport per week
  • BMI between 20 and 25 kg/m/m

Exclusion Criteria:

  • eating disorders,
  • dieting or fasting
  • restrained (score >9), disinhibited (score >11) or hungry subjects (score >9), according to the Three-Factor Eating Questionnaire general healthiness,
  • food-snacking (more than twice a day),
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00986492

Sponsors and Collaborators
University Hospital, Caen
Centre Hospitalier Universitaire Dijon
Investigators
Principal Investigator: Pierre Denise, MD, PhD University Hospital, Caen
  More Information

No publications provided by University Hospital, Caen

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Pr Pierre Denise, University Hospital, Caen
ClinicalTrials.gov Identifier: NCT00986492     History of Changes
Other Study ID Numbers: 2009-A00297-50
Study First Received: September 24, 2009
Last Updated: September 29, 2009
Health Authority: France: Afssaps - Agence française de sécurité sanitaire des produits de santé (Saint-Denis)

Keywords provided by University Hospital, Caen:
Sleep deprivation
Food intake
Motor activity
Normal, healthy subjects

Additional relevant MeSH terms:
Sleep Deprivation
Dyssomnias
Sleep Disorders
Nervous System Diseases
Neurologic Manifestations
Signs and Symptoms
Mental Disorders

ClinicalTrials.gov processed this record on September 30, 2014