Text Size

Immunohistochemical (IHC) Scoring for Receptors Expression in Breast Tissues

The recruitment status of this study is unknown because the information has not been verified recently.
Verified September 2009 by Applied Spectral Imaging Ltd..
Recruitment status was  Active, not recruiting
Sponsor:
Information provided by:
Applied Spectral Imaging Ltd.
ClinicalTrials.gov Identifier:
NCT00978276
First received: September 15, 2009
Last updated: NA
Last verified: September 2009
History: No changes posted
  Purpose

The purpose of this study is the identification and classification of human tissues and cytology specimens and elements therein.

Computer aided technology to assist the pathologists to identify, quantify, characterize and report their findings with regards to one or more diagnoses they should perform. In particular and for example: the scoring of the number of elements and their protein (antibody) expression level within a paraffin embedded tissue section.


Condition
Breast Cancer

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Retrospective
Official Title: Concordance Study for Over Expression Level of Antibodies Within Breast Tissues

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Applied Spectral Imaging Ltd.:

Biospecimen Retention:   Samples Without DNA

Paraffin embedded tissue sections of the breast


Enrollment: 150
Study Start Date: May 2006
  Eligibility

Ages Eligible for Study:   20 Years and older
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

The breast samples were taken from female patients after tru cut biopsies, lumpectomies or mastectomies. Paraffin embedded blocks were prepared from the specimens out of which sections were stained immunohistochemically with the Vision Bio Systems mouse monoclonal antibodies for Estrogen Receptor (NCL-ER-6F11) and Progesterone Receptor (NCL-PGR-312). All stages were performed under the routine procedure of the hospital laboratory.

Criteria

Inclusion Criteria:

  • Well stained paraffin embedded tissue specimens

Exclusion Criteria:

  • Fade away slides
  Contacts and Locations
No Contacts or Locations Provided
  More Information

No publications provided

Responsible Party: Tsafrir Kolatt, Applied Spectral Imaging Ltd.
ClinicalTrials.gov Identifier: NCT00978276     History of Changes
Other Study ID Numbers: ASI-IHC
Study First Received: September 15, 2009
Last Updated: September 15, 2009
Health Authority: Israel: Ministry of Health

Keywords provided by Applied Spectral Imaging Ltd.:
Receptors
Immunohistochemistry
Breast
Over expression of Hormone receptors in carcinoma of the breast sues

Additional relevant MeSH terms:
Breast Neoplasms
Neoplasms by Site
Neoplasms
Breast Diseases
Skin Diseases

ClinicalTrials.gov processed this record on May 21, 2013