Adipocytokines and Polycystic Ovary Syndrome (PCOS)

This study has been completed.
Sponsor:
Collaborators:
Statens Serum Institut
Aarhus University Hospital
Information provided by:
Hvidovre University Hospital
ClinicalTrials.gov Identifier:
NCT00975832
First received: September 10, 2009
Last updated: NA
Last verified: September 2009
History: No changes posted
  Purpose

Inflammation may play a role in the development of polycystic ovary syndrome (PCOS). In this study, the investigators investigated the expression of different mediators of inflammation in fatty tissue and in blood in women with and without PCOS.


Condition
Polycystic Ovary Syndrome

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Cross-Sectional
Official Title: Adipose Expression of Leptin, Adiponectin and IL-6, and Plasma Levels of Adipocytokines in Lean and Obese Women With PCOS

Resource links provided by NLM:


Further study details as provided by Hvidovre University Hospital:

Enrollment: 60
Groups/Cohorts
women with polycystic ovary syndrome
women without polycystic ovary syndrome
women from 18-40 years of age

  Eligibility

Ages Eligible for Study:   18 Years to 40 Years
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

36 women (17 lean and 19 obese)with PCOS and 24 (8 lean and 16 obese) control women

Criteria

Inclusion Criteria:

  • Women with PCOS were included according to the Rotterdam diagnostic criteria for PCOS. Control women met none of the criteria for PCOS

Exclusion Criteria:

  • Oc´s within the last three months, or other medication known to alter glucose/insulin metabolism
  • Other known chronic diseases
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

No Contacts or Locations Provided
  More Information

No publications provided by Hvidovre University Hospital

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Pernille Fog Svendsen, MD, Copenhagen University Hospital, Hvidovre
ClinicalTrials.gov Identifier: NCT00975832     History of Changes
Other Study ID Numbers: PSvendsen
Study First Received: September 10, 2009
Last Updated: September 10, 2009
Health Authority: Denmark: Ethics Committee

Keywords provided by Hvidovre University Hospital:
The independent effect of PCOS and obesity on adipose expression and plasma levels of adipocytokines

Additional relevant MeSH terms:
Polycystic Ovary Syndrome
Syndrome
Ovarian Cysts
Cysts
Neoplasms
Ovarian Diseases
Adnexal Diseases
Genital Diseases, Female
Gonadal Disorders
Endocrine System Diseases
Disease
Pathologic Processes

ClinicalTrials.gov processed this record on September 22, 2014