Oral Contraceptive (OC) Progestin Dose and Breast Proliferation
The purpose of this research study is to gain a better understanding of the changes that may occur in the breast when a woman uses an oral contraceptive (birth control pill). Some research indicates that women who use birth control pills with lower amounts of progestin (a hormone in the birth control pill) may have lower breast cell growth than women who use birth control pills with a higher amount of progestin; this research will examine that in detail.
Drug: Oral Contraceptive: Ortho-Novum® 1/35
Drug: Oral Contraceptive: Ovcon Fe®
|Study Design:||Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Basic Science
|Official Title:||Evaluating the Effect of Oral Contraceptive Progestin Dose on Breast Epithelial Cell Proliferation|
- To measure breast cell proliferation levels between the two oral contraceptive dose groups. [ Designated as safety issue: No ]
|Study Start Date:||August 2007|
|Primary Completion Date:||November 2008 (Final data collection date for primary outcome measure)|
Active Comparator: Ortho-Novum® 1/35
Ortho-Novum® 1/35 is an oral contraceptive that contains more progestin.
|Drug: Oral Contraceptive: Ortho-Novum® 1/35|
Active Comparator: Ovcon Fe®
Ovcon Fe® is an oral contraceptive that contains less progestin.
|Drug: Oral Contraceptive: Ovcon Fe®|
Please refer to this study by its ClinicalTrials.gov identifier: NCT00972439
|United States, California|
|Los Angeles County Hospital|
|Los Angelses, California, United States, 90033|
|Principal Investigator:||DeShawn Taylor, M.D.||University of Southern California|