Cancer Pain Single Nucleotide Polymorphisms (SNPs)
This study is currently recruiting participants.
Verified June 2011 by Erasmus Medical Center
Sponsor:
Erasmus Medical Center
Information provided by:
Erasmus Medical Center
ClinicalTrials.gov Identifier:
NCT00956878
First received: August 10, 2009
Last updated: June 21, 2011
Last verified: June 2011
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Purpose
Cancer pain is common in advanced cancer patients. Opioids are the mainstay of treatment in cancer pain. Responsiveness to and tolerability of opioids is, amongst others, determined by small variations in human DNA. Using blood samples from clinically well-defined cancer pain patients, the investigators are going to analyze single nucleotide polymorphisms (SNPs) in genes that are known to be involved in responsiveness to opioids and sensitivity to pain.
| Condition |
|---|
|
Cancer Pain |
| Study Type: | Observational |
| Study Design: | Observational Model: Case-Only Time Perspective: Prospective |
| Official Title: | Storage and Analysis of Patient Blood-samples for Cancer Pain Research |
Resource links provided by NLM:
Further study details as provided by Erasmus Medical Center:
Biospecimen Retention: Samples With DNA
Whole Blood
| Estimated Enrollment: | 300 |
| Study Start Date: | September 2008 |
| Estimated Study Completion Date: | September 2012 |
| Estimated Primary Completion Date: | September 2012 (Final data collection date for primary outcome measure) |
| Groups/Cohorts |
|---|
| Cancer Pain Patients |
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Non-Probability Sample |
Study Population
Cancer pain patients in a large university hospital
Criteria
Inclusion Criteria:
- Cancer pain patients
Exclusion Criteria:
- Patients not able to provide informed consent
Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00956878
Locations
| Netherlands | |
| Erasmus MC, Centrumlocatie en Daniel den Hoed | Recruiting |
| Rotterdam, Zuid-Holland, Netherlands, 3000CA | |
| Contact: Joost L Jongen, MD PhD +31107035754 j.jongen@erasmusmc.nl | |
| Contact: Peter A Sillevis-Smitt, MD PhD +317033327 p.sillevissmitt@erasmusmc.nl | |
| Principal Investigator: Joost L Jongen, MD PhD | |
Sponsors and Collaborators
Erasmus Medical Center
Investigators
| Principal Investigator: | Joost L Jongen, MD PhD | Erasmus MC |
More Information
Additional Information:
No publications provided
| Responsible Party: | Joost L.M. Jongen, MD PhD, Erasmus MC |
| ClinicalTrials.gov Identifier: | NCT00956878 History of Changes |
| Other Study ID Numbers: | MEC2008-166 |
| Study First Received: | August 10, 2009 |
| Last Updated: | June 21, 2011 |
| Health Authority: | Netherlands: Dutch Health Care Inspectorate |
Keywords provided by Erasmus Medical Center:
|
Cancer Pain SNP |
ClinicalTrials.gov processed this record on May 16, 2013