Etiology, Epidemiology and Prognostics of Acute Kidney Injury (AKI)
Recruitment status was Recruiting
- To investigate the etiology, epidemiology and prognostic factors of acute kidney injury.
- To find out risk factors that relate with the prognosis of acute kidney injury,focusing on inflammation, oxidative stress and nutritional status.
- To study on the relationship between gene polymorphism and prognosis of acute kidney injury.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||The Study of Etiology, Epidemiology and Prognostic Factors of Acute Kidney Injury|
- renal function survival rate days in the hospital days in the ICU [ Time Frame: discharg from hospital, 28days,90days ] [ Designated as safety issue: Yes ]
Biospecimen Retention: Samples Without DNA
1ml whole blood and 1ml serum will obtained within 24 hour after AKI for hematological and biochemistry analyze.
|Study Start Date:||April 2009|
|Estimated Study Completion Date:||August 2012|
|Estimated Primary Completion Date:||December 2011 (Final data collection date for primary outcome measure)|
to investigate the relationship between preexisting malnutrition and adverse outcomes in patients with AKI
- Several nutritional assessment methods such as anthropometric, clinical and biochemical evaluations have been used; however, no single indicator is considered to be a "gold standard."
- to evaluate the association of serum nutritional variables and prognosis of acute kidney injury
- Given the different half-lives of serum nutritional markers, we hypothesized that the utility of serum nutritional variables as prognostic predictors may differ in early death (<7 days) and late death (>7 days, <28 days) patients.
|Contact: Feng Ding, firstname.lastname@example.org|
|Shanghai, China, 200040|
|Contact: Feng Ding, professor 86-02152888135 email@example.com|
|Principal Investigator:||Feng Ding, professor||Huashan Hospital|