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Plasma Pharmacokinetics of Alkylresorcinol Metabolites; New Candidate Biomarkers for Whole Grain Rye and Wheat Intake (Rye-kinetics)

This study has been completed.
Sponsor:
Collaborators:
Samfundet Folkhälsan
Sigrid Jusélius Foundation
Information provided by:
Helsinki University
ClinicalTrials.gov Identifier:
NCT00953836
First received: August 5, 2009
Last updated: NA
Last verified: August 2009
History: No changes posted
  Purpose

The purpose of this study is to investigate the kinetics of two known alkylresorcinol metabolites in human subjects after intake of high-fiber rye bread. Whole grain rye is the most abundant source of alkylresorcinols.


Condition
Kinetics of Alkylresorcinol Metabolites

Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: Kinetic Study of Two Known Alkylresorcinol Metabolites in Human Subjects After the Intake of Rye Fiber, the Most Abundant Source of Alkylresorcinols in Diet.

Resource links provided by NLM:

MedlinePlus related topics: Dietary Fiber
U.S. FDA Resources

Further study details as provided by Helsinki University:

Enrollment: 15
Study Start Date: March 2009
Study Completion Date: May 2009
Primary Completion Date: April 2009 (Final data collection date for primary outcome measure)
  Eligibility

Ages Eligible for Study:   20 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

healthy, free-living females and males

Criteria

Inclusion Criteria:

  • Healthy, volunteer

Exclusion Criteria:

  • Hemoglobin below 125 mmol/L in females and below 135 mmol/L in males use of antibiotics within 3 months before entering the study
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00953836

Locations
Finland
Folkhälsan Research Center
Helsinki, Finland, 00250
Sponsors and Collaborators
Helsinki University
Samfundet Folkhälsan
Sigrid Jusélius Foundation
Investigators
Study Director: Matti J Tikkanen, M.D., prof. Department of Medicine, University of Helsinki, Helsinki, Finland
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00953836     History of Changes
Other Study ID Numbers: 22/13/03/00/09
Study First Received: August 5, 2009
Last Updated: August 5, 2009
Health Authority: Finland: Ethics Committee

Keywords provided by Helsinki University:
kinetics
alkylresorcinol metabolites
rye fiber

ClinicalTrials.gov processed this record on May 19, 2013