Assessment of Hemodynamic Response in Surgery of Circumcision in Children
The surgery stress relives systemic inflammatory response by hormones and adrenergic receptors. When the pro-inflammatory mediator is higher than anti-inflammatory response, the physiologic status is impaired and the patient is more susceptible an infection and cardiovascular collapse. The anesthesia can abolish or minimize the surgery stress, improved more safety to the patient.
This study is a double blind controlled trial with 40 patients divided in two groups (EMLA and Dorsal Penile Nerve Block - DPNB) submitted a standard inhalator anesthesia and postectomy surgery by Plastbell®. The investigators will be observe heart rate, respiratory rate, arterial pressure, involuntary movements during the surgery and pain in the pos-operatory.
With this study, the investigators can define what tactic (EMLA or DPNB) associated a general anesthesia is more effective to relive the pain when children are submitted a postectomy by Plastbell®.
|Study Design:||Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind (Outcomes Assessor)
Primary Purpose: Treatment
|Official Title:||Assessment of Hemodynamic Response and Pos-operatory Pain in Surgery of Circumcision in Children|
- local anesthesia relieve the circumcision pain [ Time Frame: per-operatory; 1h and 24h pos-operatory ] [ Designated as safety issue: Yes ]
- local anesthesia relieve the circumcision pos-operatory pain [ Time Frame: 1h and 24h pos-operatory ] [ Designated as safety issue: Yes ]
|Study Start Date:||March 2009|
|Study Completion Date:||June 2009|
|Primary Completion Date:||March 2009 (Final data collection date for primary outcome measure)|
|Active Comparator: anaesthesia, circumcision||
circumcision by plastbell
Please refer to this study by its ClinicalTrials.gov identifier: NCT00943475
|federal University of Juiz de Fora|
|Juiz de Fora, Minas gerais, Brazil, 36036-900|
|Principal Investigator:||Jose murillo B Netto, Doctor||Federal University of Juiz de Fora|