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Adolescent Daughters' Response and Adjustment to Maternal Breast Cancer

This study has been terminated.
(due to slow accrual and lack of funding)
Sponsor:
Collaborator:
Information provided by:
New York University School of Medicine
ClinicalTrials.gov Identifier:
NCT00933088
First received: July 2, 2009
Last updated: June 3, 2011
Last verified: June 2011
  Purpose

The aims of this study are to determine the differential coping strategies used by adolescent daughters whose mothers have breast cancer, and how this relates to the stress responses they exhibit.


Condition Intervention
Breast Cancer
Other: questionnaires

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Cross-Sectional
Official Title: Adolescent Daughters' Response and Adjustment to Maternal Breast Cancer

Resource links provided by NLM:


Further study details as provided by New York University School of Medicine:

Primary Outcome Measures:
  • adolescent coping strategies and relationship to the stress response [ Time Frame: not more than one year past mother's diagnosis and treatment ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • adolescent coping strategies by age [ Time Frame: not more than one year past mother's diagnosis and treatment ] [ Designated as safety issue: No ]
  • adolescent strategies by quality of maternal-adolescent relationship [ Time Frame: not more than one year past her diagnosis and treatment ] [ Designated as safety issue: No ]

Enrollment: 43
Study Start Date: June 2008
Study Completion Date: October 2009
Primary Completion Date: October 2009 (Final data collection date for primary outcome measure)
Intervention Details:
    Other: questionnaires

    The study instruments will be given in the following order to the adolescent daughters: 1. Responses to Stress questionnaire; 2. Inventory of Peer and Family Attachment; 3. Youth Self-Report; and, 4. Adolescent data form.

    Mothers will be asked to complete data form.

Detailed Description:

The aims of this study are to determine the differential coping strategies used by adolescent daughters whose mothers have breast cancer, and how this relates to the stress responses they exhibit. Adolescent age, and their relationship with their mothers will also be examined in relation to their coping. This group of adolescent daughters has reported a 25% increased rate of stress responses, specifically anxiety and depression, than a normative sample and than sons. They additionally report emotional distress and worries, and fear engaging in health promoting activities. Forty percent of adolescent daughters who are initially diagnosed with depression, like those whose mothers have breast cancer, will experience a second bout of depression, and 70% of those will have a relapse in adulthood. The strategies that adolescents use to cope with stress are potentially important mediators of the impact of stress on current and future adjustment. Yet little is known about the differential coping strategies used when adolescent daughters are faced with their mothers' breast cancer, and how these mediate that impact. Additionally, the generalizability of the research findings to date is limited due to the inclusion of largely Caucasian, middle-income families in the samples.

Many cancer centers in the United States provide psychosocial support services for the over 200,000 women newly diagnosed with breast cancer each year. There are few supportive care services however that target the coping of their adolescent daughters with the stress of their mother's breast cancer. Before developing these services we need to understand more about which coping strategies can mediate the stress of mothers' breast cancer and be included in any interventions. With the increased risk that these daughters face of acquiring breast cancer, developing fear about health screening, and potentially facing life-long depression, it is imperative to understand more about the coping strategies and factors that can mediate the stressfulness of this event. This cross-sectional, correlational study will target 90 adolescent daughters and their mothers with breast cancer recruited through the New York University Medical Cancer Center (NYUMC) and Bellevue Hospital/New York City Health and Hospitals Corporation (NYCHHC) cancer clinics. A contribution of this study to the research to date includes an active outreach to include the minority population. Data collection will include data sheets for mother and daughter demographic information and history, and instruments that target adolescent daughters, the different coping strategies they use, and their level of adjustment or distress with the maternal disease within the first year following diagnosis. Ultimately, the knowledge gained from this study will lead to the development of interventions that target coping and promote adjustment in this vulnerable group.

  Eligibility

Ages Eligible for Study:   13 Years to 19 Years
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

Adoelscent girls between the ages of 13 and 19 years; with a mother who was diagnosed with localized breast cancer (Stage II,II), who is not more than one year past her diagnosis and treatment, and attends the NYUMC or NYCHHC Cancer Center clinics.

Criteria

Inclusion Criteria:

  • For mothers:

    • women at any age
    • diagnosed with localized breast cancer
    • not more than one year past the initial breast cancer diagnosis and treatment
    • attending the New York University Medical Center (NYUMC) Cancer Center and/or Clinics for breast cancer treatment or follow-up
    • have a daughter between the ages of 13 and 19
    • where there are more than one adolescent daughter, all daughters can be included
  • For daughters:

    • adolescent girls between the ages of 13 and 19 years
    • with a mother who was diagnosed with localized breast cancer (Stage II,II), who is not more than one year past her diagnosis and treatment, and attends the NYUMC or NYCHHC Cancer Center clinics

Exclusion Criteria:

  • For mothers:

    • women who have recurrent breast cancer disease
    • have a second cancer diagnoses
    • have another chronic illness that they are currently being treated for
  • For daughters:

    • adolescent girls under the age of 13 years or over the age of 19
    • have been diagnosed previously with cancer themselves
    • have a chronic illness they are currently undergoing treatment for
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00933088

Locations
United States, New York
Bellevue Hospital Center
New York, New York, United States, 10016
New York University Cancer Center
New York, New York, United States, 10016
Sponsors and Collaborators
New York University School of Medicine
Investigators
Principal Investigator: Yelena Novik, MD New York University School of Medicine
  More Information

No publications provided

Responsible Party: Yelena Novik, MD, NYU Cancer Institute
ClinicalTrials.gov Identifier: NCT00933088     History of Changes
Other Study ID Numbers: NYU 08-072
Study First Received: July 2, 2009
Last Updated: June 3, 2011
Health Authority: United States: Institutional Review Board

Keywords provided by New York University School of Medicine:
adolescent coping strategies
stress response
breast cancer

Additional relevant MeSH terms:
Breast Neoplasms
Breast Diseases
Neoplasms
Neoplasms by Site
Skin Diseases

ClinicalTrials.gov processed this record on November 20, 2014