Biospecimen Repository for Cardiac Arrhythmias at the Cleveland Clinic
Recruitment status was Recruiting
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Purpose
The long-term objective of this research is to find genes and biologic pathways causing arrhythmia syndromes and other diseases or conditions. In order to achieve this objective the investigators will collect comprehensive phenotypic data and corresponding blood and/or tissue samples into a biorepository registry of patients, presenting for cardiac arrhythmia evaluation and/or treatment, and control subjects without arrhythmias. This biorepository will be composed of two parts: 1) An Arrhythmia Biorepository of blood and tissue from patients undergoing arrhythmia procedures, cardiac surgery, or inpatient or outpatient evaluations for arrhythmias, and 2) A Collaborative Sample Biorepository for deidentified samples and data from outside institutions and clinical trials.
| Condition |
|---|
|
Arrhythmias, Cardiac |
| Study Type: | Observational |
| Study Design: | Observational Model: Case Control Time Perspective: Prospective |
| Official Title: | Cleveland Clinic Arrhythmia Biospecimen Repository (Cleveland Clinic Arrhythmia BioBank) |
- Various Arrhythmias [ Time Frame: Indefinite ] [ Designated as safety issue: No ]
Biospecimen Retention: Samples With DNA
Biospecimens to be collected: DNA, RNA, plasma, & serum. Also tissue may be collected.
| Estimated Enrollment: | 2000 |
| Study Start Date: | March 2009 |
| Groups/Cohorts |
|---|
|
Arrhythmias
Patients with arrhythmias
|
|
Control Subjects
Subjects that do not have a history of cardiac arrhythmias.
|
Detailed Description:
One time blood draw and follow up in one year.
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | Yes |
| Sampling Method: | Non-Probability Sample |
Patients undergoing arrhythmia procedures, cardiac surgery or inpatient or outpatient evaluations for arrhythmias at the Cleveland Clinic or from outside collaborative institutions or from other clinical trials.
Inclusion Criteria:
- Male or female at least 18 years old
- Subjects with a history of or current cardiac arrhythmia, family members of subjects with cardiac arrhythmias, or no cardiac arrhythmia if a Control Subject.
Exclusion Criteria:
- Subjects previously enrolled in the Arrhythmia BioBank
Contacts and Locations| Contact: Mina K. Chung, MD | 216.444.2290 | chungm@ccf.org |
| Contact: Diana I. Bauer, BS | 216.444.9066 | bauerd@ccf.org |
| United States, Ohio | |
| Cleveland Clinic Foundation | Recruiting |
| Cleveland, Ohio, United States, 44195 | |
| Principal Investigator: Mina K. Chung, MD | |
| Sub-Investigator: David R. Van Wagoner, Ph.D. | |
| Sub-Investigator: Jonathan D. Smith, Ph.D. | |
| Sub-Investigator: John Barnard, Ph.D. | |
| Principal Investigator: | Mina K. Chung, MD | The Cleveland Clinic |
More Information
No publications provided
| Responsible Party: | Mina K. Chung, MD, Cleveland Clinic Foundation |
| ClinicalTrials.gov Identifier: | NCT00921986 History of Changes |
| Other Study ID Numbers: | 09-176 |
| Study First Received: | June 15, 2009 |
| Last Updated: | June 1, 2010 |
| Health Authority: | United States: Institutional Review Board |
Keywords provided by The Cleveland Clinic:
|
genetics biorepository cardiac death atrial fibrillation ventricular fibrillation ventricular tachycardia supraventricular tachycardias |
premature ventricular complexes premature atrial complexes atrioventricular and intraventricular blocks sinus node dysfunction syncope vasovagal reactivity postural orthostatic tachycardia syndrome |
Additional relevant MeSH terms:
|
Arrhythmias, Cardiac Heart Diseases Cardiovascular Diseases Pathologic Processes |
ClinicalTrials.gov processed this record on May 23, 2013