Ultrastructural Changes of Trabeculectomy Specimens in Patients With Uveitic Secondary Glaucoma

This study has been completed.
Sponsor:
Collaborator:
University of Erlangen-Nürnberg Medical School
Information provided by:
St. Franziskus Hospital
ClinicalTrials.gov Identifier:
NCT00917670
First received: June 9, 2009
Last updated: July 21, 2010
Last verified: July 2010
  Purpose

Ultrastructural analysis of trabeculectomy specimens of patients with uveitic secondary glaucoma.

To evaluate morphological changes and to compare to primary open angle glaucoma patients.


Condition
Uveitis
Secondary Glaucoma

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective

Resource links provided by NLM:


Further study details as provided by St. Franziskus Hospital:

Primary Outcome Measures:
  • morphological changes [ Time Frame: after surgery ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples With DNA

trabeculectomy specimens including trabecular meshwork and Schlemms canal


Estimated Enrollment: 10
Study Start Date: May 2009
Study Completion Date: December 2009
Primary Completion Date: September 2009 (Final data collection date for primary outcome measure)
  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Patients with uveitic secondary glaucoma in need of surgical intervention.

Criteria

Inclusion Criteria:

  • secondary uveitic glaucoma
  • IOP > 24 mmhg with topical and/or systemic therapy
  • need for surgical intervention to control IOP
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00917670

Locations
Germany
Department of Anatomy II at University of Erlangen, Germany
Erlangen, Germany
Sponsors and Collaborators
St. Franziskus Hospital
University of Erlangen-Nürnberg Medical School
  More Information

Additional Information:
No publications provided

Responsible Party: Department of Ophthalmology at St. Franziskus Hospital
ClinicalTrials.gov Identifier: NCT00917670     History of Changes
Other Study ID Numbers: 2009-200-f-S-
Study First Received: June 9, 2009
Last Updated: July 21, 2010
Health Authority: Germany: Ministry of Health

Keywords provided by St. Franziskus Hospital:
trabecular meshwork
electron microscopy

Additional relevant MeSH terms:
Glaucoma
Uveitis
Chorioretinitis
Ocular Hypertension
Eye Diseases
Uveal Diseases
Retinitis
Retinal Diseases
Choroiditis
Choroid Diseases
Uveitis, Posterior
Panuveitis

ClinicalTrials.gov processed this record on July 26, 2014