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Prevention of Potentially Inappropriate Prescribing in Late Life Using Screening Tool of Older Persons' Potentially Inappropriate Prescriptions (STOPP) and Screening Tool to Alert Doctors to Right Treatment (START) Criteria

The recruitment status of this study is unknown because the information has not been verified recently.
Verified October 2009 by Cork University Hospital.
Recruitment status was  Active, not recruiting
Sponsor:
Information provided by:
Cork University Hospital
ClinicalTrials.gov Identifier:
NCT00915824
First received: June 4, 2009
Last updated: October 28, 2009
Last verified: October 2009
History of Changes
  Purpose

Potentially inappropriate prescribing is common in older patients and encompasses overuse, misuse and underuse of medications. Potentially inappropriate prescribing is associated with negative outcomes including adverse drug events and hospitalization.

STOPP (Screening Tool of Older Person's potentially inappropriate Prescriptions) and START (Screening Tool to Alert doctors to Right Treatment) is a new screening tool designed to detect instances of potentially inappropriate medication use and under-prescribing of clinically indicated medications in older patients. The purpose of this study is to determine whether clinical implementation of STOPP/START criteria in hospitalized older patients is effective in improving prescribing quality.


Condition Intervention Phase
Healthy
 Other: STOPP/START criteria
 Phase 4

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Official Title: Prevention of Potentially Inappropriate Prescribing in Late Life Using STOPP (Screening Tool of Older Persons' Potentially Inappropriate Prescriptions) and START (Screening Tool to Alert Doctors to Right i.e. Appropriate Indicated Treatment): A Randomized Controlled Trial.

Further study details as provided by Cork University Hospital:

Primary Outcome Measures:
  • Appropriateness of prescribing using the Medication Appropriateness Index and the Assessment of Underutilization of Medication Tool [ Time Frame: Measured on admission, discharge and at 2, 4 and 6 months post-discharge ] [ Designated as safety issue: Yes ]

Secondary Outcome Measures:
  • Composite health resource utilization including hospital readmission and primary care consultations [ Time Frame: at 2, 4 and 6 months post-discharge ] [ Designated as safety issue: No ]

Enrollment: 400
Study Start Date: November 2007
Estimated Study Completion Date: June 2009
Primary Completion Date: June 2009 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: STOPP/START intervention
STOPP/START intervention group
 Other: STOPP/START criteria
Application of STOPP/START criteria to the patient's prescription and diagnostic information with subsequent written recommendation on pharmaceutical care to the patient's medical team

  Eligibility

Ages Eligible for Study:   65 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • All patients aged 65 years and older admitted to the general medical services of Cork University Hospital, Cork, Ireland

Exclusion Criteria:

  • Patient admitted to a geriatric medicine service, psychiatry of old age service or clinical pharmacology service, or under review of these services during the previous 12 months
  • Critically ill patient (admitted to the intensive care unit)
  • Terminally ill patient
  • Refusal of patient or hospital physician to participate
  • No time for the research physician to enrol the patient within 3 days of admission
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00915824

Locations
Ireland
Cork University Hospital
Cork, Ireland
Sponsors and Collaborators
Cork University Hospital
Investigators
Principal Investigator: Paul Gallagher, MB MRCPI Cork University Hospital
Study Director: Denis O'Mahony, MD FRCPI Cork University Hospital
  More Information

No publications provided

Responsible Party: Dr. Paul Gallagher, Clinical Research Fellow, Department of Geriatric Medicine, Cork University Hospital
ClinicalTrials.gov Identifier: NCT00915824     History of Changes
Other Study ID Numbers: CRT2006029
Study First Received: June 4, 2009
Last Updated: October 28, 2009
Health Authority: Ireland: Ministry of Health

Keywords provided by Cork University Hospital:
Drug therapy
Prescribing
Appropriateness
Randomized controlled trial
 STOPP/START criteria
Appropriateness of prescribing in older patients
Prescription Drugs

ClinicalTrials.gov processed this record on May 19, 2013