Pathways Linking Reduced Sleep Duration and Quality to Obesity Risk

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
University of Chicago
ClinicalTrials.gov Identifier:
NCT00915707
First received: June 3, 2009
Last updated: September 4, 2013
Last verified: September 2013
  Purpose

This study is designed to study the pathways through which short sleep duration or poor sleep quality can lead to an increased risk of developing diabetes and obesity.


Condition Intervention
Obesity
Diabetes
Other: Baseline
Other: Sleep restriction
Other: Reduced Sleep Quality

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single Blind (Subject)
Official Title: Pathways Linking Reduced Sleep Duration and Quality to Obesity Risk

Resource links provided by NLM:


Further study details as provided by University of Chicago:

Primary Outcome Measures:
  • Disposition Index reflecting Diabetes Risk as a result of decreased sleep duration and/or quality. [ Time Frame: 3 months ] [ Designated as safety issue: No ]

Enrollment: 23
Study Start Date: January 2007
Study Completion Date: July 2012
Primary Completion Date: July 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Baseline
Subjects are tested under normal sleep conditions for carbohydrate metabolism and appetite regulation.
Other: Baseline
Subjects are allowed time in bed for sleep as their usual time at home.
Experimental: Sleep restriction
Subjects are tested under sleep restriction for carbohydrate metabolism and appetite regulation.
Other: Sleep restriction
Subjects sleep is reduced to 4.5 hours in bed for 4 nights.
Experimental: Reduced sleep quality
Subjects are tested under a poor sleep quality condition for carbohydrate metabolism and appetite regulation.
Other: Reduced Sleep Quality
Subjects sleep quality is reduced for 4 nights.

  Eligibility

Ages Eligible for Study:   18 Years to 30 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Normal weight
  • Healthy
  • Normal sleep times

Exclusion Criteria:

  • Sleep disorders
  • Overweight
  • Diabetes
  • Other health conditions
  • Excessive caffeine and alcohol intake
  • Smoking
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00915707

Locations
United States, Illinois
The University of Chicago
Chicago, Illinois, United States, 60637
Sponsors and Collaborators
University of Chicago
Investigators
Principal Investigator: Esra Tasali, MD University of Chicago
  More Information

No publications provided

Responsible Party: University of Chicago
ClinicalTrials.gov Identifier: NCT00915707     History of Changes
Other Study ID Numbers: 14916B
Study First Received: June 3, 2009
Last Updated: September 4, 2013
Health Authority: United States: Institutional Review Board

Keywords provided by University of Chicago:
obesity
diabetes, risk
obesity, diabetes risk related to sleep

Additional relevant MeSH terms:
Obesity
Overnutrition
Nutrition Disorders
Overweight
Body Weight
Signs and Symptoms

ClinicalTrials.gov processed this record on September 30, 2014