Ventrointermediate Nucleus (VIM DBS) and Working Memory (WMVIM)

This study is enrolling participants by invitation only.
Sponsor:
Information provided by:
Washington University School of Medicine
ClinicalTrials.gov Identifier:
NCT00906412
First received: May 19, 2009
Last updated: June 8, 2009
Last verified: June 2009
  Purpose

This is part of a larger study for which participants have already completed memory and thinking tests. In this study, investigators are trying to learn how deep-brain stimulation affects memory skills in essential tremor (ET) patients. We are especially trying to figure out how stimulation on each side of the brain may affect working memory.


Condition
Essential Tremor

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Cross-Sectional
Official Title: VIM DBS and Working Memory

Resource links provided by NLM:


Further study details as provided by Washington University School of Medicine:

Estimated Enrollment: 50
Study Start Date: September 2006
Estimated Study Completion Date: September 2013
Groups/Cohorts
ET Group
Total of 25 participants with ET
Controls
25 controls without ET

  Eligibility

Ages Eligible for Study:   40 Years to 70 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Washington University School of Medicine Movement Disorder Clinic

Criteria

Inclusion Criteria:

ET PATIENTS:

  • Clinical diagnosis of essential tremor affecting the upper extremities.
  • Previous unilateral or bilateral DBS of the VIM
  • Ages 40 -70
  • A useable pre-surgical MR scan

CONTROLS:

  • Spouse or acquaintance of enrolled patient participant
  • Ages 40 - 70

Exclusion Criteria:

ET PATIENTS:

  • Clinical evidence of other neurological conditions
  • Significant psychiatric condition

CONTROLS:

  • Clinical evidence of other neurological conditions
  • Significant psychiatric condition
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00906412

Locations
United States, Missouri
Washington University School of Medicine
St. Louis, Missouri, United States, 63110
Sponsors and Collaborators
Washington University School of Medicine
Investigators
Principal Investigator: Hershey Tamara, PhD Washington University Early Recognition Center
  More Information

No publications provided

Responsible Party: Tamara Hershey, Ph.D., Washington University School of Medicine
ClinicalTrials.gov Identifier: NCT00906412     History of Changes
Other Study ID Numbers: 06-0732
Study First Received: May 19, 2009
Last Updated: June 8, 2009
Health Authority: United States: Institutional Review Board

Keywords provided by Washington University School of Medicine:
Essential Tremor

Additional relevant MeSH terms:
Essential Tremor
Movement Disorders
Central Nervous System Diseases
Nervous System Diseases

ClinicalTrials.gov processed this record on September 18, 2014