Ventrointermediate Nucleus (VIM DBS) and Working Memory - Full Text View

Ventrointermediate Nucleus (VIM DBS) and Working Memory (WMVIM)

This study is enrolling participants by invitation only.

First Received: May 19, 2009 Last Updated: June 8, 2009 History of Changes

Sponsor:	Washington University School of Medicine
Information provided by:	Washington University School of Medicine
ClinicalTrials.gov Identifier:	NCT00906412

Purpose

This is part of a larger study for which participants have already completed memory and thinking tests. In this study, investigators are trying to learn how deep-brain stimulation affects memory skills in essential tremor (ET) patients. We are especially trying to figure out how stimulation on each side of the brain may affect working memory.

Condition
Essential Tremor

Study Type:	Observational
Study Design:	Case Control, Cross-Sectional
Official Title:	VIM DBS and Working Memory

Resource links provided by NLM:

Genetics Home Reference related topics: essential tremor familial paroxysmal nonkinesigenic dyskinesia

MedlinePlus related topics: Memory Tremor

U.S. FDA Resources

Further study details as provided by Washington University School of Medicine:

Biospecimen Retention: None Retained

Biospecimen Description:

Estimated Enrollment:	50
Study Start Date:	September 2006
Estimated Study Completion Date:	September 2013

Groups/Cohorts
ET Group Total of 25 participants with ET
Controls 25 controls without ET

Eligibility

Ages Eligible for Study:	40 Years to 70 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes
Sampling Method:	Non-Probability Sample

Study Population

Washington University School of Medicine Movement Disorder Clinic

Criteria

Inclusion Criteria:

ET PATIENTS:

Clinical diagnosis of essential tremor affecting the upper extremities.
Previous unilateral or bilateral DBS of the VIM
Ages 40 -70
A useable pre-surgical MR scan

CONTROLS:

Spouse or acquaintance of enrolled patient participant
Ages 40 - 70

Exclusion Criteria:

ET PATIENTS:

Clinical evidence of other neurological conditions
Significant psychiatric condition

CONTROLS:

Clinical evidence of other neurological conditions
Significant psychiatric condition

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00906412

Locations

United States, Missouri
Washington University School of Medicine
St. Louis, Missouri, United States, 63110

Sponsors and Collaborators

Washington University School of Medicine

Investigators

Principal Investigator:

Hershey Tamara, PhD

Washington University School of Medicine

More Information

No publications provided

Responsible Party:	Washington University School of Medicine ( Tamara Hershey, Ph.D. )
Study ID Numbers:	06-0732
Study First Received:	May 19, 2009
Last Updated:	June 8, 2009
ClinicalTrials.gov Identifier:	NCT00906412 History of Changes
Health Authority:	United States: Institutional Review Board

Keywords provided by Washington University School of Medicine:

Essential Tremor

Additional relevant MeSH terms:

Signs and Symptoms
Essential Tremor
Movement Disorders
Nervous System Diseases

Central Nervous System Diseases
Neurologic Manifestations
Dyskinesias
Tremor

ClinicalTrials.gov processed this record on February 08, 2010