Transversus Abdominis Plane Block For Renal Transplant Recipients

This study has been completed.
Sponsor:
Information provided by:
Royal Liverpool and Broadgreen University Hospitals NHS Trust
ClinicalTrials.gov Identifier:
NCT00905957
First received: May 19, 2009
Last updated: August 17, 2011
Last verified: October 2010
  Purpose

The purpose of this study is to evaluate the efficacy of a local anaesthetic injection in the plane between the abdominal muscles in reducing the amount of pain relief required after surgery.


Condition Intervention
Disorder Related to Renal Transplantation
Pain
Procedure: TAP block
Procedure: TAP block with placebo

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Transversus Abdominis Plane Block For Renal Transplant Recipients: A Randomized Controlled Double-blinded Study

Resource links provided by NLM:


Further study details as provided by Royal Liverpool and Broadgreen University Hospitals NHS Trust:

Primary Outcome Measures:
  • Morphine consumption in first 24 hours after renal transplantation [ Time Frame: 24 hours ] [ Designated as safety issue: Yes ]

Enrollment: 52
Study Start Date: October 2010
Study Completion Date: June 2011
Primary Completion Date: June 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: Transversus abdominis plane (TAP) Group
Patients will receive a TAP block using a local anaesthetic agent after induction of anaesthesia
Procedure: TAP block
TAP block using 20 ml of a local anaesthetic agent will be used in the treatment group
Placebo Comparator: Control Group
Patients will receive a TAP block using a placebo after induction of anaesthesia
Procedure: TAP block with placebo
TAP block using a placebo after induction of anaesthesia

Detailed Description:

The aim of this study is to evaluate the efficacy of transversus abdominis plane block in reducing the morphine requirements after renal transplantation.

  Eligibility

Ages Eligible for Study:   18 Years to 75 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • renal transplant recipients
  • 18 to 75 years

Exclusion Criteria:

  • allergy to local anaesthetics
  • chronic pain
  • refusal
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00905957

Locations
United Kingdom
Royal Liverpool and Broadgreen University Hospitals
Liverpool, Merseyside, United Kingdom, L7 8XP
Sponsors and Collaborators
Royal Liverpool and Broadgreen University Hospitals NHS Trust
  More Information

No publications provided

Responsible Party: KARIM MUKHTAR, ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS
ClinicalTrials.gov Identifier: NCT00905957     History of Changes
Other Study ID Numbers: 3818
Study First Received: May 19, 2009
Last Updated: August 17, 2011
Health Authority: United Kingdom: Research Ethics Committee

Keywords provided by Royal Liverpool and Broadgreen University Hospitals NHS Trust:
transversus abdominis plane block
relief

ClinicalTrials.gov processed this record on September 16, 2014